Comprehensive lipidomics reveals phenotypic differences in hepatic lipid turnover in ALD and NAFLD during alcohol intoxication.

Israelsen, Mads; Kim, Min; Suvitaival, Tommi; Madsen, Bjørn Stæhr; Hansen, Camilla Dalby; Torp, Nikolaj; Trost, Kajetan; Thiele, Maja; Hansen, Torben; Legido-Quigley, Cristina; Krag, Aleksander

Israelsen, Mads; Kim, Min; Suvitaival, Tommi; Madsen, Bjørn Stæhr; Hansen, Camilla Dalby; Torp, Nikolaj; Trost, Kajetan; Thiele, Maja; Hansen, Torben; Legido-Quigley, Cristina; Krag, Aleksander.

Afiliação

Israelsen M; Department of Gastroenterology and Hepatology, Odense University Hospital, Odense C, Denmark.
Kim M; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense C, Denmark.
Suvitaival T; OPEN Open Patient data Explorative Network, Faculty of Health Sciences, University of Southern Denmark, Odense C, Denmark.
Madsen BS; Steno Diabetes Center Copenhagen, Gentofte, Denmark.
Hansen CD; Steno Diabetes Center Copenhagen, Gentofte, Denmark.
Torp N; Department of Gastroenterology and Hepatology, Odense University Hospital, Odense C, Denmark.
Trost K; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense C, Denmark.
Thiele M; Department of Gastroenterology and Hepatology, Odense University Hospital, Odense C, Denmark.
Hansen T; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense C, Denmark.
Legido-Quigley C; Department of Gastroenterology and Hepatology, Odense University Hospital, Odense C, Denmark.
Krag A; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense C, Denmark.

JHEP Rep ; 3(5): 100325, 2021 Oct.

Article em En | MEDLINE | ID: mdl-34401690

Palavras-chave

ALD, alcohol-related liver disease; ALT, alanine aminotransferase; AST, asparagine aminotransferase; Alcohol; CTL, healthy control; Cer, ceramide; DG, diglyceride; Ethanol; FFA, free fatty acid; Fatty acids; GGT, gamma-glutamyl transferase; HOMA-IR, Homeostatic Model Assessment of Insulin Resistance; Heavy drinking; HexCer, hexosylceramide; LPC, lysophosphatidylcholine; LPE, lysophosphatidylethanolamine; LacCer, lactosylceramides; Lipidomics; Liver disease; Lysophosphatidylcholines; NAFLD, non-alcoholic fatty liver disease; P-glucose, plasma glucose; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PI, phosphatidylinositol; PLA2, phospholipase A2; QC, quality control; SHexCer, sulfatides hexosylceramide; SM, sphingomyelin; TE, transient elastography; TG, triglyceride; Triglycerides

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google