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Secretome screening reveals immunomodulating functions of IFNα-7, PAP and GDF-7 on regulatory T-cells.
Ding, Mei; Malhotra, Rajneesh; Ottosson, Tomas; Lundqvist, Magnus; Mebrahtu, Aman; Brengdahl, Johan; Gehrmann, Ulf; Bäck, Elisabeth; Ross-Thriepland, Douglas; Isaksson, Ida; Magnusson, Björn; Sachsenmeier, Kris F; Tegel, Hanna; Hober, Sophia; Uhlén, Mathias; Mayr, Lorenz M; Davies, Rick; Rockberg, Johan; Schiavone, Lovisa Holmberg.
Afiliação
  • Ding M; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden. mei.ding@astrazeneca.com.
  • Malhotra R; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Ottosson T; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Lundqvist M; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
  • Mebrahtu A; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
  • Brengdahl J; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden.
  • Gehrmann U; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Bäck E; Mechanistic Biology and Profiling, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden.
  • Ross-Thriepland D; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge, UK.
  • Isaksson I; Sample Management, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden.
  • Magnusson B; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden.
  • Sachsenmeier KF; Translational Medicine, Oncology R&D, AstraZeneca, Boston, USA.
  • Tegel H; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
  • Hober S; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
  • Uhlén M; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
  • Mayr LM; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge, UK.
  • Davies R; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge, UK.
  • Rockberg J; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
  • Schiavone LH; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden. lovisa.holmberg.schiavone@astrazeneca.com.
Sci Rep ; 11(1): 16767, 2021 08 18.
Article em En | MEDLINE | ID: mdl-34408239
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interferon-alfa / Linfócitos T Reguladores / Proteínas Morfogenéticas Ósseas / Fatores de Diferenciação de Crescimento / Proteínas Associadas a Pancreatite / Fatores Imunológicos Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interferon-alfa / Linfócitos T Reguladores / Proteínas Morfogenéticas Ósseas / Fatores de Diferenciação de Crescimento / Proteínas Associadas a Pancreatite / Fatores Imunológicos Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article