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Loss of tyrosine catabolic enzyme HPD promotes glutamine anaplerosis through mTOR signaling in liver cancer.
Tong, Man; Wong, Tin-Lok; Zhao, Hongzhi; Zheng, Yuanyuan; Xie, Yu-Nong; Li, Cheuk-Hin; Zhou, Lei; Che, Noélia; Yun, Jing-Ping; Man, Kwan; Lee, Terence Kin-Wah; Cai, Zongwei; Ma, Stephanie.
Afiliação
  • Tong M; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China. Electronic address: caroltm@hku.hk.
  • Wong TL; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Zhao H; State Key Laboratory of Environmental and Biological Analysis, Hong Kong Baptist University, Hong Kong, China.
  • Zheng Y; State Key Laboratory of Environmental and Biological Analysis, Hong Kong Baptist University, Hong Kong, China.
  • Xie YN; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Li CH; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Zhou L; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Che N; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Yun JP; Department of Pathology, Sun Yat-Sen University Cancer Center, Guangzhou, China.
  • Man K; The University of Hong Kong-Shenzhen Hospital, Shenzhen, China; Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Lee TK; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China.
  • Cai Z; State Key Laboratory of Environmental and Biological Analysis, Hong Kong Baptist University, Hong Kong, China. Electronic address: zwcai@hkbu.edu.hk.
  • Ma S; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China; The University of Hong Kong-Shenzhen Hospital, Shenzhen, China. Electronic address: stefma@hku.hk.
Cell Rep ; 36(8): 109617, 2021 08 24.
Article em En | MEDLINE | ID: mdl-34433044
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tirosina / Serina-Treonina Quinases TOR / Glutamina / 4-Hidroxifenilpiruvato Dioxigenase / Neoplasias Hepáticas Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tirosina / Serina-Treonina Quinases TOR / Glutamina / 4-Hidroxifenilpiruvato Dioxigenase / Neoplasias Hepáticas Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article