Leveraging the attention mechanism to improve the identification of DNA N6-methyladenine sites.

Zhang, Ying; Liu, Yan; Xu, Jian; Wang, Xiaoyu; Peng, Xinxin; Song, Jiangning; Yu, Dong-Jun

Zhang, Ying; Liu, Yan; Xu, Jian; Wang, Xiaoyu; Peng, Xinxin; Song, Jiangning; Yu, Dong-Jun.

Afiliação

Zhang Y; School of Computer Science and Engineering at Nanjing University of Science and Technology, 200 Xiaolingwei, Nanjing 210094, China.
Liu Y; School of Computer Science and Engineering at Nanjing University of Science and Technology, 200 Xiaolingwei, Nanjing 210094, China.
Xu J; School of Computer Science and Engineering, Nanjing University of Science and Technology, 200 Xiaolingwei, Nanjing 210094, China.
Wang X; Monash Biomedicine Discovery Institute and the Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia.
Peng X; Monash Biomedicine Discovery Institute and the Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia.
Song J; Monash Biomedicine Discovery Institute and the Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia.
Yu DJ; School of Computer Science and Engineering, Nanjing University of Science and Technology, 200 Xiaolingwei, Nanjing 210094, China.

Brief Bioinform ; 22(6)2021 11 05.

Article em En | MEDLINE | ID: mdl-34459479

Assuntos

Adenosina/análogos & derivados; Biologia Computacional/métodos; Metilação de DNA; DNA/genética; Epigenômica/métodos; DNA/química; Aprendizado Profundo

Palavras-chave

6mA; DNA modification; LSTM; attention interpretation; deep learning; self-attention mechanism

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Adenosina / Biologia Computacional / Metilação de DNA / Epigenômica Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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