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The pan-PPAR agonist lanifibranor reduces development of lung fibrosis and attenuates cardiorespiratory manifestations in a transgenic mouse model of systemic sclerosis.
Derrett-Smith, Emma; Clark, Kristina E N; Shiwen, Xu; Abraham, David J; Hoyles, Rachel K; Lacombe, Olivier; Broqua, Pierre; Junien, Jean Louis; Konstantinova, Irena; Ong, Voon H; Denton, Christopher P.
Afiliação
  • Derrett-Smith E; Centre for Rheumatology and Connective Tissue Diseases, UCL Division of Medicine, Rowland Hill St., London, NW3 2PF, UK.
  • Clark KEN; Centre for Rheumatology and Connective Tissue Diseases, UCL Division of Medicine, Rowland Hill St., London, NW3 2PF, UK.
  • Shiwen X; Centre for Rheumatology and Connective Tissue Diseases, UCL Division of Medicine, Rowland Hill St., London, NW3 2PF, UK.
  • Abraham DJ; Centre for Rheumatology and Connective Tissue Diseases, UCL Division of Medicine, Rowland Hill St., London, NW3 2PF, UK.
  • Hoyles RK; Churchill Hospital, Oxford, OX3 7LE, UK.
  • Lacombe O; Inventiva, 21121, Daix, France.
  • Broqua P; Inventiva, 21121, Daix, France.
  • Junien JL; Inventiva, 21121, Daix, France.
  • Konstantinova I; Inventiva, 21121, Daix, France.
  • Ong VH; Centre for Rheumatology and Connective Tissue Diseases, UCL Division of Medicine, Rowland Hill St., London, NW3 2PF, UK.
  • Denton CP; Centre for Rheumatology and Connective Tissue Diseases, UCL Division of Medicine, Rowland Hill St., London, NW3 2PF, UK. c.denton@ucl.ac.uk.
Arthritis Res Ther ; 23(1): 234, 2021 09 06.
Article em En | MEDLINE | ID: mdl-34488870

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Escleroderma Sistêmico Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Escleroderma Sistêmico Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article