Your browser doesn't support javascript.
loading
The Mechanobiology of Vascular Remodeling in the Aging Lung.
Dieffenbach, Paul B; Aravamudhan, Aja; Fredenburgh, Laura E; Tschumperlin, Daniel J.
Afiliação
  • Dieffenbach PB; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
  • Aravamudhan A; Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.
  • Fredenburgh LE; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
  • Tschumperlin DJ; Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.
Physiology (Bethesda) ; 37(1): 28-38, 2022 01 01.
Article em En | MEDLINE | ID: mdl-34514871
ABSTRACT
Aging is accompanied by declining lung function and increasing susceptibility to lung diseases. The role of endothelial dysfunction and vascular remodeling in these changes is supported by growing evidence, but underlying mechanisms remain elusive. In this review we summarize functional, structural, and molecular changes in the aging pulmonary vasculature and explore how interacting aging and mechanobiological cues may drive progressive vascular remodeling in the lungs.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Vasculares / Remodelação Vascular Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Vasculares / Remodelação Vascular Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article