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Phase I study of cediranib, an oral VEGFR inhibitor, in combination with selumetinib, an oral MEK inhibitor, in patients with advanced solid malignancies.
Hubbard, Joleen M; Yin, Jun; Schenk, Erin L; Qin, Rui; Reid, Joel M; Strand, Carrie; Fiskum, Jack; Menefee, Michael; Lin, Grace; Doyle, L Austin; Ivy, Percy; Erlichman, Charles; Adjei, Alex; Haluska, Paul; Costello, Brian A.
Afiliação
  • Hubbard JM; Division of Medical Oncology, Mayo Clinic, Rochester, MN, 55905, USA.
  • Yin J; Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Schenk EL; Division of Medical Oncology, Mayo Clinic, Rochester, MN, 55905, USA.
  • Qin R; Division of Medical Oncology, University of Colorado, Anschutz Medical Campus, Aurora, CO, 80045, USA.
  • Reid JM; Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Strand C; Division of Oncology Research, Mayo Clinic, Rochester, MN, 55905, USA.
  • Fiskum J; Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Menefee M; Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Lin G; VA Medical Center, Washington, DC, 20422, USA.
  • Doyle LA; Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 55905, USA.
  • Ivy P; Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of fHealth, Bethesda, MD, 20892, USA.
  • Erlichman C; Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of fHealth, Bethesda, MD, 20892, USA.
  • Adjei A; Division of Medical Oncology, Mayo Clinic, Rochester, MN, 55905, USA.
  • Haluska P; Division of Medical Oncology, Mayo Clinic, Rochester, MN, 55905, USA.
  • Costello BA; Division of Medical Oncology, Mayo Clinic, Rochester, MN, 55905, USA.
Invest New Drugs ; 40(1): 115-123, 2022 02.
Article em En | MEDLINE | ID: mdl-34515877
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Benzimidazóis / Neoplasias / Antineoplásicos Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Benzimidazóis / Neoplasias / Antineoplásicos Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article