Long non-coding RNA SLC2A1-AS1 induced by GLI3 promotes aerobic glycolysis and progression in esophageal squamous cell carcinoma by sponging miR-378a-3p to enhance Glut1 expression.

Liu, Hongtao; Zhang, Qing; Song, Yinsen; Hao, Yibin; Cui, Yunxia; Zhang, Xin; Zhang, Xueying; Qin, Yue; Zhu, Guangzhao; Wang, Feng; Dang, Jinghan; Ma, Shanshan; Zhang, Yanting; Guo, Wenna; Li, Shenglei; Guan, Fangxia; Fan, Tianli

Liu, Hongtao; Zhang, Qing; Song, Yinsen; Hao, Yibin; Cui, Yunxia; Zhang, Xin; Zhang, Xueying; Qin, Yue; Zhu, Guangzhao; Wang, Feng; Dang, Jinghan; Ma, Shanshan; Zhang, Yanting; Guo, Wenna; Li, Shenglei; Guan, Fangxia; Fan, Tianli.

Afiliação

Liu H; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China. liuht1230@126.com.
Zhang Q; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Song Y; Translational Medicine Research Center, Zhengzhou People's Hospital, Zhengzhou, 450003, Henan, China.
Hao Y; Translational Medicine Research Center, Zhengzhou People's Hospital, Zhengzhou, 450003, Henan, China.
Cui Y; Translational Medicine Research Center, Zhengzhou People's Hospital, Zhengzhou, 450003, Henan, China.
Zhang X; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Zhang X; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Qin Y; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Zhu G; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Wang F; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Dang J; Institute of Genomic Medicine, College of Pharmacy, Jinan University, Guangzhou, 510632, Guangdong, China.
Ma S; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), College of pharmacy, Jinan University, Guangzhou, 510632, Guangdong, China.
Zhang Y; Department of Clinical Medicine, Zhengzhou University, Zhengzhou, 450052, Henan, China.
Guo W; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Li S; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Guan F; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Fan T; Department of Pathology, the First Affiliated Hospital of Zhengzhou University, 40 Daxue Road, Zhengzhou, 450052, Henan, China. lslbljys@126.com.

J Exp Clin Cancer Res ; 40(1): 287, 2021 Sep 13.

Article em En | MEDLINE | ID: mdl-34517880

Assuntos

Neoplasias Esofágicas/metabolismo; Carcinoma de Células Escamosas do Esôfago/metabolismo; Transportador de Glucose Tipo 1/biossíntese; Glicólise/genética; MicroRNAs/metabolismo; Proteínas do Tecido Nervoso/metabolismo; RNA Longo não Codificante/metabolismo; Proteína Gli3 com Dedos de Zinco/metabolismo; Animais; Linhagem Celular Tumoral; Proliferação de Células/fisiologia; Progressão da Doença; Neoplasias Esofágicas/genética; Neoplasias Esofágicas/patologia; Carcinoma de Células Escamosas do Esôfago/genética; Carcinoma de Células Escamosas do Esôfago/patologia; Feminino; Xenoenxertos; Humanos; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; MicroRNAs/genética; Proteínas do Tecido Nervoso/genética; Prognóstico; Proteína Gli3 com Dedos de Zinco/genética

Palavras-chave

Esophageal squamous cell carcinoma; Glucose transporter 1; Glycolysis; SLC2A1-AS1; miR-378a-3p

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / MicroRNAs / Transportador de Glucose Tipo 1 / RNA Longo não Codificante / Proteína Gli3 com Dedos de Zinco / Carcinoma de Células Escamosas do Esôfago / Glicólise / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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