Identification of SARS-CoV-2 RNA-dependent RNA polymerase inhibitors from the major phytochemicals of <i>Nigella sativa</i>: An <i>in silico</i> approach.

Mir, Shabir Ahmad; Firoz, Ahmad; Alaidarous, Mohammed; Alshehri, Bader; Bin Dukhyil, Abdul Aziz; Banawas, Saeed; Alsagaby, Suliman A; Alturaiki, Wael; Bhat, Gulzar Ahmad; Kashoo, Faizan; Abdel-Hadi, Ahmad M

Identification of SARS-CoV-2 RNA-dependent RNA polymerase inhibitors from the major phytochemicals of Nigella sativa: An in silico approach.

Mir, Shabir Ahmad; Firoz, Ahmad; Alaidarous, Mohammed; Alshehri, Bader; Bin Dukhyil, Abdul Aziz; Banawas, Saeed; Alsagaby, Suliman A; Alturaiki, Wael; Bhat, Gulzar Ahmad; Kashoo, Faizan; Abdel-Hadi, Ahmad M.

Afiliação

Mir SA; Department of Medical Laboratory Sciences, College of Applied Medical Science, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Firoz A; Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Ssaudi Arabia.
Alaidarous M; Department of Medical Laboratory Sciences, College of Applied Medical Science, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Alshehri B; Health and Basic Sciences Research Center, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Bin Dukhyil AA; Department of Medical Laboratory Sciences, College of Applied Medical Science, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Banawas S; Department of Medical Laboratory Sciences, College of Applied Medical Science, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Alsagaby SA; Department of Medical Laboratory Sciences, College of Applied Medical Science, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Alturaiki W; Health and Basic Sciences Research Center, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Bhat GA; Department of Biomedical Sciences, Oregon State University, Corvallis, OR 97331, USA.
Kashoo F; Department of Medical Laboratory Sciences, College of Applied Medical Science, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Abdel-Hadi AM; Department of Medical Laboratory Sciences, College of Applied Medical Science, Majmaah University, Al Majmaah 11952, Saudi Arabia.

Saudi J Biol Sci ; 29(1): 394-401, 2022 Jan.

Article em En | MEDLINE | ID: mdl-34518755

Palavras-chave

COVID-19, coronavirus disease 2019; Docking; Drug; GUI, graphical user interface; In silico; MERS-CoV, Middle East respiratory syndrome coronavirus; Nigella Sativa; Phytochemical; RCSB PDB, Research Collaboratory for Structural Bioinformatics Protein Data Bank; RMSD, root mean square deviation; RMSF, root mean square fluctuations; RNA polymerase; RdRp, RNA-dependent RNA polymerase; SARS-CoV-2; SARS-CoV-2, severe acute respiratory syndrome-coronavirus-2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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