Cell culture-based production of defective interfering influenza A virus particles in perfusion mode using an alternating tangential flow filtration system.

Hein, Marc D; Chawla, Anshika; Cattaneo, Maurizio; Kupke, Sascha Y; Genzel, Yvonne; Reichl, Udo

Hein, Marc D; Chawla, Anshika; Cattaneo, Maurizio; Kupke, Sascha Y; Genzel, Yvonne; Reichl, Udo.

Afiliação

Hein MD; Chair of Bioprocess Engineering, Otto-Von-Guericke-University Magdeburg, Magdeburg, Germany.
Chawla A; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.
Cattaneo M; Institute of Pharmacy, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Kupke SY; Artemis Biosystems, Cambridge, MA, USA.
Genzel Y; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany. kupke@mpi-magdeburg.mpg.de.
Reichl U; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany. genzel@mpi-magdeburg.mpg.de.

Appl Microbiol Biotechnol ; 105(19): 7251-7264, 2021 Oct.

Article em En | MEDLINE | ID: mdl-34519855

Assuntos

Vírus da Influenza A; Técnicas de Cultura de Células; Humanos; Perfusão

Palavras-chave

Alternating tangential flow filtration (ATF); Antiviral; Bioreactor; Cell culturebased production; Defective interfering particles (DIPs); Influenza A virus; Perfusion cultivation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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