Your browser doesn't support javascript.
loading
Quick-Wee versus bladder stimulation to collect midstream urine from precontinent infants under 1 year of age: a study protocol for a randomised controlled trial (ES.Stimquick.U).
Marchal, Sarah; Janicot, Jade; Salicis, Julie; Demonchy, Diane; Herisse, Anne-Laure; Olla, Marco; Rancurel, Anne; Haas, Hervé; Bérard, Etienne; Bréaud, Jean; Bernardor, Julie; Ribet, Chloé; Freyssinet, Emma; Donzeau, Dominique; Desmontils, Jonathan; Schori-Fortier, Clara; Fontas, Eric; Tran, Antoine.
Afiliação
  • Marchal S; Service des Urgences Pédiatriques, Hôpitaux Pédiatriques de Nice CHU-LENVAL, Nice, France marchal.s@pediatrie-chulenval-nice.fr.
  • Janicot J; Service de Pédiatrie, Centre Hospitalier de Grasse, Grasse, France.
  • Salicis J; Service des Urgences Pédiatriques, Hôpitaux Pédiatriques de Nice CHU-LENVAL, Nice, France.
  • Demonchy D; Service des Urgences Pédiatriques, Hôpitaux Pédiatriques de Nice CHU-LENVAL, Nice, France.
  • Herisse AL; Service des Urgences Pédiatriques, Hôpitaux Pédiatriques de Nice CHU-LENVAL, Nice, France.
  • Olla M; Service des Urgences Pédiatriques, Hôpitaux Pédiatriques de Nice CHU-LENVAL, Nice, France.
  • Rancurel A; Service des Urgences Pédiatriques, Hôpitaux Pédiatriques de Nice CHU-LENVAL, Nice, France.
  • Haas H; Service de Pédiatrie, Centre Hospitalier Princesse Grace, Monaco.
  • Bérard E; Service de Néphrologie Pédiatrique, Centre Hospitalier Universitaire de Nice, Nice, France.
  • Bréaud J; Service de Chirurgie Pédiatrique, Hôpitaux Pédiatriques de Nice CHU-LENVAL, Nice, France.
  • Bernardor J; Service de Néphrologie Pédiatrique, Centre Hospitalier Universitaire de Nice, Nice, France.
  • Ribet C; Service des Urgences Pédiatriques, Hôpitaux Pédiatriques de Nice CHU-LENVAL, Nice, France.
  • Freyssinet E; Service des Urgences Pédiatriques, Hôpitaux Pédiatriques de Nice CHU-LENVAL, Nice, France.
  • Donzeau D; Délégation à la Recherche Clinique et à l'Innovation, Centre Hospitalier Universitaire de Nice, Nice, France.
  • Desmontils J; Service de Pédiatrie, Centre Hospitalier de Grasse, Grasse, France.
  • Schori-Fortier C; Service de Pédiatrie, Centre Hospitalier d Antibes Juan les Pins, Antibes, France.
  • Fontas E; Délégation à la Recherche Clinique et à l'Innovation, Centre Hospitalier Universitaire de Nice, Nice, France.
  • Tran A; Service des Urgences Pédiatriques, Hôpitaux Pédiatriques de Nice CHU-LENVAL, Nice, France.
BMJ Open ; 11(9): e046324, 2021 09 16.
Article em En | MEDLINE | ID: mdl-34531206
INTRODUCTION: Urinary tract infections occur in around 1%-4% of boys and 3%-8% of girls under 2 years old. Diagnosis is difficult because of non-specific symptoms and the risk of urine analysis contamination depending on the sampling method used for precontinent infants. The American Academy of Pediatrics recommend transurethral catheterisation and suprapubic aspiration because of a low contamination rate but these techniques are invasive. On the other hand, while the National Institute for Health and Care Excellence advocate clean catch urine for its minimal invasiveness and acceptable contamination rate, it is difficult to accomplish in precontinent infants. Two recent methods have been described: the Quick-Wee method by Kaufman et al (suprapubic stimulation with cold saline-soaked gauze); and bladder stimulation by Herreros et al then by Tran et al (pubic tapping alternating with lumbar massage). This study aims to compare the effectiveness in collecting midstream urine by bladder stimulation vs the Quick-Wee method in infants under 1 year, before walking. METHODS AND ANALYSIS: This study is a multicentre randomised controlled trial of 230 infants under 1 year and before walking who need urine analysis, conducted in four paediatric emergency departments in France. Patients will be randomised into two groups: bladder stimulation and Quick-Wee method.The primary endpoint will be the success rate of voiding at least 2 mL of urine in less than 5 min.Secondary outcomes are the time to collect at least 2 mL of urine, comfort, quality of urine and the risk factors associated with failure of the two techniques. ETHICS AND DISSEMINATION: The study protocol was approved by the French national ethic committee (consultative committee of the protection of persons). The results of the study will be published in a peer-reviewed journal. TRIAL REGISTRATION NUMBER: Clinical Trials Registry - NCT04587999. DATE AND PROTOCOL VERSION IDENTIFIER: October 2020, V.1.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Urinárias / Bexiga Urinária Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies / Risk_factors_studies Limite: Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Urinárias / Bexiga Urinária Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies / Risk_factors_studies Limite: Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article