Molecularly engineered carrier-free co-delivery nanoassembly for self-sensitized photothermal cancer therapy.

Shan, Xinzhu; Zhang, Xuanbo; Wang, Chen; Zhao, Zhiqiang; Zhang, Shenwu; Wang, Yuequan; Sun, Bingjun; Luo, Cong; He, Zhonggui

Shan, Xinzhu; Zhang, Xuanbo; Wang, Chen; Zhao, Zhiqiang; Zhang, Shenwu; Wang, Yuequan; Sun, Bingjun; Luo, Cong; He, Zhonggui.

Afiliação

Shan X; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
Zhang X; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
Wang C; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
Zhao Z; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
Zhang S; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
Wang Y; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
Sun B; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
Luo C; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China. luocong@syphu.edu.cn.
He Z; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China. hezhonggui@vip.163.com.

J Nanobiotechnology ; 19(1): 282, 2021 Sep 20.

Article em En | MEDLINE | ID: mdl-34544447

Assuntos

Nanoestruturas/química; Neoplasias/tratamento farmacológico; Fármacos Fotossensibilizantes/uso terapêutico; Xantonas/química; Animais; Linhagem Celular Tumoral; Portadores de Fármacos/química; Portadores de Fármacos/metabolismo; Liberação Controlada de Fármacos; Proteínas de Choque Térmico HSP90/antagonistas & inibidores; Proteínas de Choque Térmico HSP90/metabolismo; Humanos; Lasers; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Neoplasias/patologia; Fármacos Fotossensibilizantes/química; Fármacos Fotossensibilizantes/metabolismo; Terapia Fototérmica; Ratos; Ratos Sprague-Dawley; Distribuição Tecidual; Transplante Heterólogo; Xantonas/metabolismo; Xantonas/uso terapêutico

Palavras-chave

Dual-drug nanoassembly; HSP90 inhibitor; Photothermal photosensitizers; Self-sensitized photothermal therapy; Thermoresistance

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fármacos Fotossensibilizantes / Xantonas / Nanoestruturas / Neoplasias Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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