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Safety and preliminary efficacy of sequential multiple ascending doses of solnatide to treat pulmonary permeability edema in patients with moderate-to-severe ARDS-a randomized, placebo-controlled, double-blind trial.
Schmid, Benedikt; Kredel, Markus; Ullrich, Roman; Krenn, Katharina; Lucas, Rudolf; Markstaller, Klaus; Fischer, Bernhard; Kranke, Peter; Meybohm, Patrick; Zwißler, Bernhard; Frank, Sandra.
Afiliação
  • Schmid B; Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Wuerzburg, Wuerzburg, Germany.
  • Kredel M; Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Wuerzburg, Wuerzburg, Germany.
  • Ullrich R; Department of Anaesthesia, General Intensive Care and Pain Medicine, Medical University of Vienna, Vienna, Austria.
  • Krenn K; Department of Anaesthesia, General Intensive Care and Pain Medicine, Medical University of Vienna, Vienna, Austria.
  • Lucas R; Vascular Biology Center, Division of Pulmonary Medicine, Medical College of Georgia, Augusta University, Augusta, USA.
  • Markstaller K; Department of Anaesthesia, General Intensive Care and Pain Medicine, Medical University of Vienna, Vienna, Austria.
  • Fischer B; Apeptico Forschung und Entwicklung GmbH, Vienna, Austria.
  • Kranke P; Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Wuerzburg, Wuerzburg, Germany. kranke_p@ukw.de.
  • Meybohm P; Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Wuerzburg, Wuerzburg, Germany.
  • Zwißler B; Department of Anesthesiology, University Hospital of Ludwig-Maximilians-University (LMU), Munich, Germany.
  • Frank S; Comprehensive Pulmonary Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany.
Trials ; 22(1): 643, 2021 Sep 20.
Article em En | MEDLINE | ID: mdl-34544463
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Edema Pulmonar / Síndrome do Desconforto Respiratório / COVID-19 Tipo de estudo: Clinical_trials / Diagnostic_studies / Guideline / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Edema Pulmonar / Síndrome do Desconforto Respiratório / COVID-19 Tipo de estudo: Clinical_trials / Diagnostic_studies / Guideline / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article