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Cerebrospinal Fluid Iron-Ferritin Ratio as a Potential Progression Marker for Parkinson's Disease.
Maass, Fabian; Michalke, Bernhard; Willkommen, Desiree; Canaslan, Sezgi; Schmitz, Matthias; Bähr, Mathias; Zerr, Inga; Lingor, Paul.
Afiliação
  • Maass F; Department of Neurology, University Medical Center Göttingen, Goettingen, Germany.
  • Michalke B; Research Unit Analytical BioGeoChemistry, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany.
  • Willkommen D; Research Unit Analytical BioGeoChemistry, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany.
  • Canaslan S; Department of Neurology, University Medical Center Göttingen, Goettingen, Germany.
  • Schmitz M; Department of Neurology, University Medical Center Göttingen, Goettingen, Germany.
  • Bähr M; DZNE, German Center for Neurodegenerative Diseases, Goettingen, Germany.
  • Zerr I; Department of Neurology, University Medical Center Göttingen, Goettingen, Germany.
  • Lingor P; Center for Biostructural Imaging of Neurodegeneration (BIN), University of Göttingen Medical Center, Göttingen, Germany.
Mov Disord ; 36(12): 2967-2969, 2021 12.
Article em En | MEDLINE | ID: mdl-34553776
ABSTRACT
Longitudinal PD CSF samples were subjected to ICP-MS and the total amount of iron and other bioelements was quantified. Additionally, ferritin and protein biomarkers of neurodegeneration were measured. Over time, mean iron levels significantly increased while levels of ferritin decreased.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Ferritinas / Ferro Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Ferritinas / Ferro Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article