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Long-term efficacy and safety of canakinumab in patients with mevalonate kinase deficiency: results from the randomised Phase 3 CLUSTER trial.
Jeyaratnam, Jerold; Simon, Anna; Calvo, Inmaculada; Constantin, Tamas; Shcherbina, Anna; Hofer, Michael; Gattorno, Marco; Martini, Alberto; Bader-Meunier, Brigitte; Vastert, Bas; Levy, Jeremy; Dekker, Elise; de Benedetti, Fabrizio; Frenkel, Joost.
Afiliação
  • Jeyaratnam J; Department of Pediatrics, University Medical Center Utrecht, Utrecht.
  • Simon A; Department of Internal Medicine, Radboud University Medical Center, Radboudumc Expertise Center for Immunodeficiency and Autoinflammation (REIA), Nijmegen, The Netherlands.
  • Calvo I; Pediatric Rheumatology Unit, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
  • Constantin T; 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary.
  • Shcherbina A; Department of Immunology, Dmitry Rogachev National Medical Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
  • Hofer M; Unité Centre Multisite Romande d'Immuno-e Rhumatologie Pediatrique, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
  • Gattorno M; Center for Autoinflammatory Diseases and Immunodeficiencies, IRCCS, G. Gaslini.
  • Martini A; University of Genoa, Genoa, Italy.
  • Bader-Meunier B; Department of Pediatric Immunology, Hematology and Rheumatology, Universite de Paris, Institut des Maladies Genetiques (IMAGINE Institute), Reference Centre for Rheumatic, AutoImmune, and Systemic Diseases in Children (RAISE), Necker Hospital, Assistance Publique-Hopitaux de Paris, Paris, France.
  • Vastert B; Department of Pediatric Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Levy J; Novartis Pharma AG, Basel, Switzerland.
  • Dekker E; Novartis Pharma AG, Basel, Switzerland.
  • de Benedetti F; Division of Rheumatology, Ospedale Pediatrico Bambino Gesù, Roma, Italy.
  • Frenkel J; Department of Pediatrics, University Medical Center Utrecht, Utrecht.
Rheumatology (Oxford) ; 61(5): 2088-2094, 2022 05 05.
Article em En | MEDLINE | ID: mdl-34554243
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Deficiência de Mevalonato Quinase Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Deficiência de Mevalonato Quinase Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article