Epinephrine levels decrease in responders after electroconvulsive therapy.
J Neural Transm (Vienna)
; 128(12): 1917-1921, 2021 12.
Article
em En
| MEDLINE
| ID: mdl-34554316
ABSTRACT
We examined potential changes in catecholamine plasma levels and cortisol serum levels in 29 patients with treatment-resistant Major Depressive Disorder (MDD) during a course of electroconvulsive therapy (ECT). Blood samples were taken at three different time points directly before (T1) and 15 min after (T2) the first ECT, and directly before the last one (T3). Patients responding to ECT had a significant decrease of the intraindividual epinephrine plasma level when both first time points (Δ T1-T2) were compared (χ2 (1) = 10.05, p = 0.002). This finding encourages further investigation in the understanding of the catecholamine-metabolism including its release and uptake in patients with treatment-resistant MDD receiving ECT.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtorno Depressivo Maior
/
Eletroconvulsoterapia
/
Transtorno Depressivo Resistente a Tratamento
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article