Mitochondrial dysfunction in a mouse model of prodromal Parkinson's disease: A metabolomic analysis.

Ikuno, Masashi; Yamakado, Hodaka; Amano, Ikuko; Hatanaka, Yusuke; Uemura, Norihito; Matsuzawa, Shu-Ichi; Takahashi, Ryosuke

Ikuno, Masashi; Yamakado, Hodaka; Amano, Ikuko; Hatanaka, Yusuke; Uemura, Norihito; Matsuzawa, Shu-Ichi; Takahashi, Ryosuke.

Afiliação

Ikuno M; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yamakado H; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan. Electronic address: yamakado@kuhp.kyoto-u.ac.jp.
Amano I; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Hatanaka Y; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Uemura N; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Matsuzawa SI; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Takahashi R; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan. Electronic address: ryosuket@kuhp.kyoto-u.ac.jp.

Neurosci Lett ; 765: 136267, 2021 11 20.

Article em En | MEDLINE | ID: mdl-34571089

Assuntos

Biomarcadores/sangue; Carnitina/análogos & derivados; Mitocôndrias/patologia; Transtornos Parkinsonianos/metabolismo; Animais; Carnitina/sangue; Modelos Animais de Doenças; Metabolômica; Camundongos; Mitocôndrias/metabolismo; Sintomas Prodrômicos

Palavras-chave

Alpha-synuclein; Biomarker; Metabolome; Mitochondria; Parkinson's disease; Prodromal Parkinson's disease

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores / Carnitina / Transtornos Parkinsonianos / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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