Tandem Mass Spectrometry as Strategy for the Selective Identification and Quantification of the Amyloid Precursor Protein Tyr682 Residue Phosphorylation Status in Human Blood Mononuclear Cells.

Reveglia, Pierluigi; Nasso, Rosarita; Angiolillo, Antonella; Lecce, Lucia; Paolillo, Carmela; De Tullio, Samantha; Gelzo, Monica; Di Costanzo, Alfonso; Matrone, Carmela; Corso, Gaetano

Reveglia, Pierluigi; Nasso, Rosarita; Angiolillo, Antonella; Lecce, Lucia; Paolillo, Carmela; De Tullio, Samantha; Gelzo, Monica; Di Costanzo, Alfonso; Matrone, Carmela; Corso, Gaetano.

Afiliação

Reveglia P; Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Nasso R; Division of Pharmacology, Department of Neuroscience, School of Medicine, University of Naples Federico II, 80131 Naples, Italy.
Angiolillo A; Centre for Research and Training in Medicine for Aging, Department of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, 86100 Campobasso, Italy.
Lecce L; Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Paolillo C; Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
De Tullio S; Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Gelzo M; CEINGE-Biotecnologie Avanzate, scarl, 80145 Naples, Italy.
Di Costanzo A; Department of Molecular Medicine and Medical Biotechnology (DMMBM), University of Naples Federico II, 80131 Naples, Italy.
Matrone C; Centre for Research and Training in Medicine for Aging, Department of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, 86100 Campobasso, Italy.
Corso G; Division of Pharmacology, Department of Neuroscience, School of Medicine, University of Naples Federico II, 80131 Naples, Italy.

Biomolecules ; 11(9)2021 08 31.

Article em En | MEDLINE | ID: mdl-34572510

Assuntos

Precursor de Proteína beta-Amiloide/sangue; Leucócitos Mononucleares/metabolismo; Fosfoproteínas/metabolismo; Espectrometria de Massas em Tandem; Tirosina/metabolismo; Sequência de Aminoácidos; Precursor de Proteína beta-Amiloide/química; Calibragem; Linhagem Celular; Humanos; Fosforilação; Reprodutibilidade dos Testes

Palavras-chave

APP Tyr682 phosphorylation; Alzheimer's disease; targeted peptide analysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Tirosina / Leucócitos Mononucleares / Precursor de Proteína beta-Amiloide / Espectrometria de Massas em Tandem Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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