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Oncogenic KRAS drives radioresistance through upregulation of NRF2-53BP1-mediated non-homologous end-joining repair.
Yang, Linlin; Shen, Changxian; Estrada-Bernal, Adriana; Robb, Ryan; Chatterjee, Moumita; Sebastian, Nikhil; Webb, Amy; Mo, Xiaokui; Chen, Wei; Krishnan, Sunil; Williams, Terence M.
Afiliação
  • Yang L; Department of Radiation Oncology, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Shen C; Department of Radiation Oncology, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Estrada-Bernal A; The Ohio State University Wexner Medical Center, Arthur G. James Comprehensive Cancer Center and Richard J. Solove Research Institute, Columbus, OH 43210, USA.
  • Robb R; The Ohio State University Wexner Medical Center, Arthur G. James Comprehensive Cancer Center and Richard J. Solove Research Institute, Columbus, OH 43210, USA.
  • Chatterjee M; The Ohio State University Wexner Medical Center, Arthur G. James Comprehensive Cancer Center and Richard J. Solove Research Institute, Columbus, OH 43210, USA.
  • Sebastian N; The Ohio State University Wexner Medical Center, Arthur G. James Comprehensive Cancer Center and Richard J. Solove Research Institute, Columbus, OH 43210, USA.
  • Webb A; The Ohio State University Wexner Medical Center, Arthur G. James Comprehensive Cancer Center and Richard J. Solove Research Institute, Columbus, OH 43210, USA.
  • Mo X; The Ohio State University Wexner Medical Center, Arthur G. James Comprehensive Cancer Center and Richard J. Solove Research Institute, Columbus, OH 43210, USA.
  • Chen W; The Ohio State University Wexner Medical Center, Arthur G. James Comprehensive Cancer Center and Richard J. Solove Research Institute, Columbus, OH 43210, USA.
  • Krishnan S; Mayo Clinic Cancer Center, Jacksonville, FL 32224, USA.
  • Williams TM; Department of Radiation Oncology, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA.
Nucleic Acids Res ; 49(19): 11067-11082, 2021 11 08.
Article em En | MEDLINE | ID: mdl-34606602

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tolerância a Radiação / Proteínas Proto-Oncogênicas p21(ras) / Neoplasias do Colo / Fator 2 Relacionado a NF-E2 / Reparo do DNA por Junção de Extremidades / Proteína 1 de Ligação à Proteína Supressora de Tumor p53 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tolerância a Radiação / Proteínas Proto-Oncogênicas p21(ras) / Neoplasias do Colo / Fator 2 Relacionado a NF-E2 / Reparo do DNA por Junção de Extremidades / Proteína 1 de Ligação à Proteína Supressora de Tumor p53 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article