lncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into the nucleus.

Liu, Hai-Ting; Zou, Yong-Xin; Zhu, Wen-Jie; Zhang, Guo-Hao; Ma, Ran-Ran; Guo, Xiang-Yu; Gao, Peng

Liu, Hai-Ting; Zou, Yong-Xin; Zhu, Wen-Jie; Zhang, Guo-Hao; Ma, Ran-Ran; Guo, Xiang-Yu; Gao, Peng.

Afiliação

Liu HT; Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Pathology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, P.R. China.
Zou YX; Department of Pathology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, P.R. China.
Zhu WJ; Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Pathology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, P.R. China.
Sen-Liu; Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Pathology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, P.R. China.
Zhang GH; Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Pathology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, P.R. China.
Ma RR; Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Pathology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, P.R. China.
Guo XY; Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Pathology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, P.R. China.
Gao P; Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Pathology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, P.R. China.

Cell Death Differ ; 29(3): 627-641, 2022 03.

Article em En | MEDLINE | ID: mdl-34608273

Assuntos

MicroRNAs; RNA Longo não Codificante; Neoplasias Gástricas; Carcinogênese/genética; Linhagem Celular Tumoral; Movimento Celular/genética; Proliferação de Células/genética; Proteínas Culina; Regulação Neoplásica da Expressão Gênica; Humanos; Metiltransferases/genética; Metiltransferases/metabolismo; MicroRNAs/genética; MicroRNAs/metabolismo; Sinais de Localização Nuclear/genética; Sinais de Localização Nuclear/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; RNA Longo não Codificante/genética; RNA Longo não Codificante/metabolismo; Fator de Transcrição Sp1/genética; Fator de Transcrição Sp1/metabolismo; Neoplasias Gástricas/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / MicroRNAs / RNA Longo não Codificante Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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