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Elevated acute phase proteins affect pharmacokinetics in COVID-19 trials: Lessons from the CounterCOVID - imatinib study.
Bartelink, Imke H; Bet, Pierre M; Widmer, Nicolas; Guidi, Monia; Duijvelaar, Erik; Grob, Bram; Honeywell, Richard; Evelo, Amanda; Tielbeek, Ivo P E; Snape, Sue D; Hamer, Henrike; Decosterd, Laurent A; Jan Bogaard, Harm; Aman, Jurjan; Swart, Eleonora L.
Afiliação
  • Bartelink IH; Department of Clinical Pharmacology and Pharmacy, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
  • Bet PM; Department of Clinical Pharmacology and Pharmacy, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
  • Widmer N; Service of Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
  • Guidi M; Specialised Centre for Emergency and Disaster Pharmacy, Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland.
  • Duijvelaar E; Pharmacy of the Eastern Vaud Hospitals, Rennaz, Switzerland.
  • Grob B; Service of Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
  • Honeywell R; Center for Research and Innovation in Clinical Pharmaceutical Sciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
  • Evelo A; Department of Pulmonary Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
  • Tielbeek IPE; Department of Clinical Pharmacology and Pharmacy, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
  • Snape SD; Department of Clinical Pharmacology and Pharmacy, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
  • Hamer H; Department of Clinical Pharmacology and Pharmacy, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
  • Decosterd LA; Department of Clinical Pharmacology and Pharmacy, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
  • Jan Bogaard H; Exvastat Ltd., Cambridge, UK.
  • Aman J; Department of Clinical Chemistry, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
  • Swart EL; Service of Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
CPT Pharmacometrics Syst Pharmacol ; 10(12): 1497-1511, 2021 12.
Article em En | MEDLINE | ID: mdl-34608769
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Fase Aguda / Inibidores de Proteínas Quinases / Mesilato de Imatinib / COVID-19 / Tratamento Farmacológico da COVID-19 Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Fase Aguda / Inibidores de Proteínas Quinases / Mesilato de Imatinib / COVID-19 / Tratamento Farmacológico da COVID-19 Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article