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Design, synthesis and mechanistic study of novel diarylpyrazole derivatives as anti-inflammatory agents with reduced cardiovascular side effects.
Amin, Noha H; Hamed, Mohammed I A; Abdel-Fattah, Maha M; Abusabaa, Ahmed H A; El-Saadi, Mohammed T.
Afiliação
  • Amin NH; Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt. Electronic address: noha.metri@pharm.bsu.edu.eg.
  • Hamed MIA; Department of Organic and Medicinal Chemistry, Faculty of Pharmacy, Fayoum University, 63514, Egypt.
  • Abdel-Fattah MM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt.
  • Abusabaa AHA; Department of Organic and Medicinal Chemistry, Faculty of Pharmacy, Fayoum University, 63514, Egypt.
  • El-Saadi MT; Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt; Department of Medicinal Chemistry, Faculty of Pharmacy, Sinai University-Kantra Branch, Egypt.
Bioorg Chem ; 116: 105394, 2021 11.
Article em En | MEDLINE | ID: mdl-34619468
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Desenho de Fármacos / Anti-Inflamatórios não Esteroides / Inibidores de Lipoxigenase / Inibidores de Ciclo-Oxigenase 2 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Desenho de Fármacos / Anti-Inflamatórios não Esteroides / Inibidores de Lipoxigenase / Inibidores de Ciclo-Oxigenase 2 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article