Targeted treatment of immune thrombocytopenia in CTLA-4 insufficiency: a case report.

Lai, Chieh Min Benjamin; Setiadi, Audi; Barlas, Angeliki; Kanani, Amin; Pourshahnazari, Persia; Leitch, Heather A; Metzger, Daniel L; Merkeley, Hayley; Biggs, Catherine M

Lai, Chieh Min Benjamin; Setiadi, Audi; Barlas, Angeliki; Kanani, Amin; Pourshahnazari, Persia; Leitch, Heather A; Metzger, Daniel L; Merkeley, Hayley; Biggs, Catherine M.

Afiliação

Lai CMB; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Setiadi A; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
Barlas A; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Kanani A; Division of Allergy and Clinical Immunology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Pourshahnazari P; Division of Allergy and Clinical Immunology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Leitch HA; Division of Hematology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Metzger DL; Division of Endocrinology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Merkeley H; Division of Hematology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Biggs CM; Division of Allergy and Clinical Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.

Br J Haematol ; 196(3): e42-e45, 2022 02.

Article em En | MEDLINE | ID: mdl-34628649

Assuntos

Antígeno CTLA-4/genética; Terapia de Alvo Molecular; Púrpura Trombocitopênica Idiopática/tratamento farmacológico; Púrpura Trombocitopênica Idiopática/etiologia; Antígeno CTLA-4/metabolismo; Humanos; Inibidores de Checkpoint Imunológico/uso terapêutico; Masculino; Terapia de Alvo Molecular/métodos; Inibidores de Proteínas Quinases/farmacologia; Inibidores de Proteínas Quinases/uso terapêutico; Púrpura Trombocitopênica Idiopática/diagnóstico; Resultado do Tratamento; Adulto Jovem

Palavras-chave

abatacept; cytotoxic T lymphocyte-associated antigen-4; immune thrombocytopenia; sirolimus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Púrpura Trombocitopênica Idiopática / Terapia de Alvo Molecular / Antígeno CTLA-4 Tipo de estudo: Diagnostic_studies Limite: Adult / Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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