GATM-Mediated Creatine Biosynthesis Enables Maintenance of FLT3-ITD-Mutant Acute Myeloid Leukemia.

Zhang, Yuan; Newsom, Kimberly J; Zhang, Mei; Kelley, Jeffry S; Starostik, Petr

Zhang, Yuan; Newsom, Kimberly J; Zhang, Mei; Kelley, Jeffry S; Starostik, Petr.

Afiliação

Zhang Y; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida.
Newsom KJ; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida.
Zhang M; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida.
Kelley JS; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida.
Starostik P; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida. starostik@pathology.ufl.edu.

Mol Cancer Res ; 20(2): 293-304, 2022 02.

Article em En | MEDLINE | ID: mdl-34635505

Assuntos

Amidinotransferases/metabolismo; Creatina/metabolismo; Leucemia Mieloide Aguda/genética; Tirosina Quinase 3 Semelhante a fms/metabolismo; Linhagem Celular Tumoral; Proliferação de Células; Humanos; Leucemia Mieloide Aguda/patologia; Mutação; Transdução de Sinais; Transfecção

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Creatina / Tirosina Quinase 3 Semelhante a fms / Amidinotransferases Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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