Photoinduced efficient synthesis of cyanoalkylsulfonylated oxindoles via sulfur dioxide insertion.
Org Biomol Chem
; 19(41): 8929-8933, 2021 10 27.
Article
em En
| MEDLINE
| ID: mdl-34636391
ABSTRACT
A visible-light-promoted radical cascade reaction of N-arylacrylamide and cyclobutanone oxime esters with sulfur dioxide insertion is established. Mainly through the exploration of the visible light wavelength, it is found that the light source has a certain influence on the formation of cyanoalkylsulfonylated oxindoles, furnishing a range of sulfones in good to excellent yields. This protocol presents good functional group compatibility and does not require transition metals, photosensitizers, external bases, or oxidants.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article