Reduced expression of dopamine D2 receptors on astrocytes in R6/1 HD mice and HD post-mortem tissue.

Harris, Kate L; Mason, Sarah L; Vallin, Benjamin; Barker, Roger A

Harris, Kate L; Mason, Sarah L; Vallin, Benjamin; Barker, Roger A.

Afiliação

Harris KL; MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, UK. Electronic address: kharris@mrc-lmb.cam.ac.uk.
Mason SL; Department of Clinical Neurosciences, John van Geest Centre for Brain Repair, E.D. Adrian Building, Forvie Site, Robinson Way, Cambridge CB2 0PY, UK.
Vallin B; Department of Clinical Neurosciences, John van Geest Centre for Brain Repair, E.D. Adrian Building, Forvie Site, Robinson Way, Cambridge CB2 0PY, UK.
Barker RA; Department of Clinical Neurosciences, John van Geest Centre for Brain Repair, E.D. Adrian Building, Forvie Site, Robinson Way, Cambridge CB2 0PY, UK; MRC-WT Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.

Neurosci Lett ; 767: 136289, 2022 01 10.

Article em En | MEDLINE | ID: mdl-34637857

Assuntos

Astrócitos/metabolismo; Hipocampo/metabolismo; Doença de Huntington/metabolismo; Receptores de Dopamina D2/metabolismo; Idoso; Animais; Autopsia; Feminino; Gliose/patologia; Hipocampo/patologia; Humanos; Doença de Huntington/patologia; Masculino; Camundongos; Camundongos Transgênicos; Pessoa de Meia-Idade

Palavras-chave

Astrocytes; Dopamine; Dopamine D2 receptor; Dopamine receptors; Huntington's disease; Neurodegeneration; Neuroscience

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Astrócitos / Receptores de Dopamina D2 / Doença de Huntington / Hipocampo Tipo de estudo: Prognostic_studies Limite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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