Knee Osteoarthritis Progression Is Delayed in Silent Information Regulator 2 Ortholog 1 Knock-in Mice.

Yamamoto, Tetsuya; Miyaji, Nobuaki; Kataoka, Kiminari; Nishida, Kyohei; Nagai, Kanto; Kanzaki, Noriyuki; Hoshino, Yuichi; Kuroda, Ryosuke; Matsushita, Takehiko

Yamamoto, Tetsuya; Miyaji, Nobuaki; Kataoka, Kiminari; Nishida, Kyohei; Nagai, Kanto; Kanzaki, Noriyuki; Hoshino, Yuichi; Kuroda, Ryosuke; Matsushita, Takehiko.

Afiliação

Yamamoto T; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Miyaji N; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Kataoka K; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Nishida K; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Nagai K; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Kanzaki N; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Hoshino Y; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Kuroda R; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Matsushita T; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.

Int J Mol Sci ; 22(19)2021 Oct 01.

Article em En | MEDLINE | ID: mdl-34639026

Assuntos

Suscetibilidade a Doenças; Osteoartrite do Joelho/etiologia; Osteoartrite do Joelho/patologia; Sirtuína 1/genética; Animais; Biomarcadores; Cartilagem Articular/metabolismo; Cartilagem Articular/patologia; Citocinas/metabolismo; Modelos Animais de Doenças; Progressão da Doença; Predisposição Genética para Doença; Mediadores da Inflamação; Meniscos Tibiais/metabolismo; Meniscos Tibiais/patologia; Meniscos Tibiais/cirurgia; Camundongos; Camundongos Transgênicos; Osteoartrite do Joelho/metabolismo; Osteoartrite do Joelho/terapia; Sirtuína 1/metabolismo

Palavras-chave

knee; knock-in mice; osteoarthritis; silent information regulator 2 ortholog 1 (SIRT1)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite do Joelho / Suscetibilidade a Doenças / Sirtuína 1 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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