Spontaneous arising of a lymphoblastoid B-cell line harbouring a pre-leukemic DNMT3A mutation in acute myeloid leukaemia cell culture.

Hayun, Michal; Szwarcwort, Moran; Rosenberg, Dina; Sahar, Dvora; Ofran, Yishai

Hayun, Michal; Szwarcwort, Moran; Rosenberg, Dina; Sahar, Dvora; Ofran, Yishai.

Afiliação

Hayun M; The Clinical Research Institute at Rambam (CRIR), Rambam Health Care Campus, Haifa, Israel.
Szwarcwort M; Virology Laboratory, Rambam Health Care Campus, Haifa, Israel.
Rosenberg D; Hematology Laboratory, Rambam Health Care Campus, Haifa, Israel.
Sahar D; Hematology Laboratory, Rambam Health Care Campus, Haifa, Israel.
Ofran Y; The Clinical Research Institute at Rambam (CRIR), Rambam Health Care Campus, Haifa, Israel.

J Cell Mol Med ; 25(22): 10778-10782, 2021 11.

Article em En | MEDLINE | ID: mdl-34651440

Assuntos

Linfócitos B/metabolismo; Linfócitos B/patologia; DNA Metiltransferase 3A/genética; Leucemia Mieloide Aguda/patologia; Mutação; DNA Metiltransferase 3A/metabolismo; Humanos; Leucemia Mieloide Aguda/etiologia; Células Tumorais Cultivadas

Palavras-chave

B-cell functions; DNMT3A; acute myeloid leukaemia; pre-leukemic mutations; spontaneously arising lymphoblastoid cell line

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos B / Leucemia Mieloide Aguda / DNA Metiltransferase 3A / Mutação Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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