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Tau in the brain interstitial fluid is fragmented and seeding-competent.
Barini, Erica; Plotzky, Gudrun; Mordashova, Yulia; Hoppe, Jonas; Rodriguez-Correa, Esther; Julier, Sonja; LePrieult, Florie; Mairhofer, Ina; Mezler, Mario; Biesinger, Sandra; Cik, Miroslav; Meinhardt, Marcus W; Ercan-Herbst, Ebru; Ehrnhoefer, Dagmar E; Striebinger, Andreas; Bodie, Karen; Klein, Corinna; Gasparini, Laura; Schlegel, Kerstin.
Afiliação
  • Barini E; AbbVie Deutschland GmbH & Co. KG , Neuroscience Discovery, Knollstrasse, Ludwigshafen, Germany. Electronic address: laura.gasparini@abbvie.com.
  • Plotzky G; AbbVie Deutschland GmbH & Co. KG , Neuroscience Discovery, Knollstrasse, Ludwigshafen, Germany.
  • Mordashova Y; AbbVie Deutschland GmbH & Co. KG, Discovery and Exploratory Statistics (DIVES), Knollstrasse, Ludwigshafen, Germany.
  • Hoppe J; AbbVie Deutschland GmbH & Co. KG , Neuroscience Discovery, Knollstrasse, Ludwigshafen, Germany.
  • Rodriguez-Correa E; AbbVie Deutschland GmbH & Co. KG , Neuroscience Discovery, Knollstrasse, Ludwigshafen, Germany.
  • Julier S; AbbVie Deutschland GmbH & Co. KG , Neuroscience Discovery, Knollstrasse, Ludwigshafen, Germany.
  • LePrieult F; AbbVie Deutschland GmbH & Co. KG, Drug Metabolism and Pharmacokinetics, Knollstrasse, Ludwigshafen, Germany.
  • Mairhofer I; AbbVie Deutschland GmbH & Co. KG, Drug Metabolism and Pharmacokinetics, Knollstrasse, Ludwigshafen, Germany.
  • Mezler M; AbbVie Deutschland GmbH & Co. KG, Drug Metabolism and Pharmacokinetics, Knollstrasse, Ludwigshafen, Germany.
  • Biesinger S; AbbVie Deutschland GmbH & Co. KG , Neuroscience Discovery, Knollstrasse, Ludwigshafen, Germany.
  • Cik M; AbbVie Deutschland GmbH & Co. KG , Neuroscience Discovery, Knollstrasse, Ludwigshafen, Germany.
  • Meinhardt MW; AbbVie Deutschland GmbH & Co. KG , Neuroscience Discovery, Knollstrasse, Ludwigshafen, Germany.
  • Ercan-Herbst E; BioMed X GmbH, Im Neuenheimer Feld, Heidelberg, Germany.
  • Ehrnhoefer DE; BioMed X GmbH, Im Neuenheimer Feld, Heidelberg, Germany; AbbVie Deutschland GmbH & Co. KG , Neuroscience Discovery, Knollstrasse, Ludwigshafen, Germany.
  • Striebinger A; AbbVie Deutschland GmbH & Co. KG , Neuroscience Discovery, Knollstrasse, Ludwigshafen, Germany.
  • Bodie K; AbbVie Deutschland GmbH & Co. KG, Preclinical Safety, Knollstrasse, Ludwigshafen, Germany.
  • Klein C; AbbVie Deutschland GmbH & Co. KG , Neuroscience Discovery, Knollstrasse, Ludwigshafen, Germany.
  • Gasparini L; AbbVie Deutschland GmbH & Co. KG , Neuroscience Discovery, Knollstrasse, Ludwigshafen, Germany. Electronic address: laura.gasparini@abbvie.com.
  • Schlegel K; AbbVie Deutschland GmbH & Co. KG , Neuroscience Discovery, Knollstrasse, Ludwigshafen, Germany. Electronic address: kerstin.schlegel@abbvie.com.
Neurobiol Aging ; 109: 64-77, 2022 01.
Article em En | MEDLINE | ID: mdl-34655982
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Proteínas tau / Tauopatias / Líquido Extracelular Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Proteínas tau / Tauopatias / Líquido Extracelular Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article