Physiologically Based Pharmacokinetic/Pharmacodynamic Model for the Treatment of Dengue Infections Applied to the Broad Spectrum Antiviral Soraphen A.

Rox, Katharina; Heyner, Maxi; Krull, Jana; Harmrolfs, Kirsten; Rinne, Valtteri; Hokkanen, Juho; Perez Vilaro, Gemma; Díez, Juana; Müller, Rolf; Kröger, Andrea; Sugiyama, Yuichi; Brönstrup, Mark

Rox, Katharina; Heyner, Maxi; Krull, Jana; Harmrolfs, Kirsten; Rinne, Valtteri; Hokkanen, Juho; Perez Vilaro, Gemma; Díez, Juana; Müller, Rolf; Kröger, Andrea; Sugiyama, Yuichi; Brönstrup, Mark.

Afiliação

Rox K; Department of Chemical Biology, Helmholtz Centre for Infection Research (HZI), Inhoffenstrasse 7, 38124 Braunschweig, Germany.
Heyner M; German Centre for Infection Research (DZIF), Partner-Site Hannover-Braunschweig, 38124 Braunschweig, Germany.
Krull J; Sugiyama Laboratory, RIKEN Baton Zone Program, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan.
Harmrolfs K; Research Group Innate Immunity and Infection, Helmholtz Centre for Infection Research (HZI), Inhoffenstrasse 7, 38124 Braunschweig, Germany.
Rinne V; Institute for Medical Microbiology and Hospital Hygiene, Otto-von-Guericke University Magdeburg, Leipziger Strasse 44, 39120 Magdeburg, Germany.
Hokkanen J; Department of Chemical Biology, Helmholtz Centre for Infection Research (HZI), Inhoffenstrasse 7, 38124 Braunschweig, Germany.
Perez Vilaro G; Department of Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland, Helmholtz Centre for Infection Research (HZI), Campus E 8.1, 66123 Saarbrücken, Germany.
Díez J; Admesope Ltd, Typpitie 1, 90620 Oulu, Finland.
Müller R; Admesope Ltd, Typpitie 1, 90620 Oulu, Finland.
Kröger A; Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Dr. Aiguader, 88, 08003 Barcelona, Spain.
Sugiyama Y; Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Dr. Aiguader, 88, 08003 Barcelona, Spain.
Brönstrup M; German Centre for Infection Research (DZIF), Partner-Site Hannover-Braunschweig, 38124 Braunschweig, Germany.

ACS Pharmacol Transl Sci ; 4(5): 1499-1513, 2021 Oct 08.

Article em En | MEDLINE | ID: mdl-34661071

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article