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Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-bind, randomised, placebo-controlled, phase 3 trial.
Kalil, Andre C; Mehta, Aneesh K; Patterson, Thomas F; Erdmann, Nathaniel; Gomez, Carlos A; Jain, Mamta K; Wolfe, Cameron R; Ruiz-Palacios, Guillermo M; Kline, Susan; Regalado Pineda, Justino; Luetkemeyer, Anne F; Harkins, Michelle S; Jackson, Patrick E H; Iovine, Nicole M; Tapson, Victor F; Oh, Myoung-Don; Whitaker, Jennifer A; Mularski, Richard A; Paules, Catharine I; Ince, Dilek; Takasaki, Jin; Sweeney, Daniel A; Sandkovsky, Uriel; Wyles, David L; Hohmann, Elizabeth; Grimes, Kevin A; Grossberg, Robert; Laguio-Vila, Maryrose; Lambert, Allison A; Lopez de Castilla, Diego; Kim, EuSuk; Larson, LuAnn; Wan, Claire R; Traenkner, Jessica J; Ponce, Philip O; Patterson, Jan E; Goepfert, Paul A; Sofarelli, Theresa A; Mocherla, Satish; Ko, Emily R; Ponce de Leon, Alfredo; Doernberg, Sarah B; Atmar, Robert L; Maves, Ryan C; Dangond, Fernando; Ferreira, Jennifer; Green, Michelle; Makowski, Mat; Bonnett, Tyler; Beresnev, Tatiana.
Afiliação
  • Kalil AC; University of Nebraska Medical Center, Omaha, NE, USA. Electronic address: akalil@unmc.edu.
  • Mehta AK; Emory University, Atlanta, GA, USA.
  • Patterson TF; University of Texas Health San Antonio, University Health System, and the South Texas Veterans Health Care System, San Antonio, TX, USA.
  • Erdmann N; University of Alabama at Birmingham, Birmingham, AL, USA.
  • Gomez CA; University of Utah, Salt Lake City, UT, USA.
  • Jain MK; University of Texas Southwestern Medical Center, Parkland Health & Hospital System, Dallas, TX, USA; UT Southwestern Medical Center, Parkland Health and Hospital System, Dallas, TX, USA.
  • Wolfe CR; Duke University, Durham, NC.
  • Ruiz-Palacios GM; Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
  • Kline S; University of Minnesota Medical School, Minneapolis, MN, USA.
  • Regalado Pineda J; Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico.
  • Luetkemeyer AF; University of California San Francisco, San Francisco, CA, USA.
  • Harkins MS; University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
  • Jackson PEH; University of Virginia, Charlottesville, VA, USA.
  • Iovine NM; University of Florida, Gainesville, FL, USA.
  • Tapson VF; Cedars Sinai Medical Center, Los Angeles, CA, USA.
  • Oh MD; Seoul National University Hospital, Seoul, Korea.
  • Whitaker JA; Baylor College of Medicine, Houston, TX, USA.
  • Mularski RA; Kaiser Permanente Northwest, Portland, OR, USA.
  • Paules CI; Pennsylvania State Health Milton S Hershey Medical Center, Hershey, PA, USA.
  • Ince D; Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
  • Takasaki J; National Center for Global Health and Medicine, Tokyo, Japan.
  • Sweeney DA; University of California San Diego, La Jolla, CA, USA.
  • Sandkovsky U; Baylor Scott & White Health, Dallas, TX, USA.
  • Wyles DL; Denver Health and Hospital Authority, Denver, CO, USA.
  • Hohmann E; Massachusetts General Hospital, Boston, MA, USA.
  • Grimes KA; Houston Methodist, Houston, TX, USA.
  • Grossberg R; Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Laguio-Vila M; University of Rochester and Rochester Regional Health, Rochester, NY, USA.
  • Lambert AA; Providence Sacred Heart Medical Center, Spokane, WA, USA.
  • Lopez de Castilla D; Evergreen Health Medical Center, Kirkland, WA, USA.
  • Kim E; Seoul National University Bundang Hospital, Seongnam, Korea.
  • Larson L; University of Nebraska Medical Center, Omaha, NE, USA.
  • Wan CR; Emory University, Atlanta, GA, USA.
  • Traenkner JJ; Emory University, Atlanta, GA, USA.
  • Ponce PO; University of Texas Health San Antonio, University Health System, and the South Texas Veterans Health Care System, San Antonio, TX, USA.
  • Patterson JE; University of Texas Health San Antonio, University Health System, and the South Texas Veterans Health Care System, San Antonio, TX, USA.
  • Goepfert PA; University of Alabama at Birmingham, Birmingham, AL, USA.
  • Sofarelli TA; University of Utah, Salt Lake City, UT, USA.
  • Mocherla S; University of Texas Southwestern Medical Center, Parkland Health & Hospital System, Dallas, TX, USA; UT Southwestern Medical Center, Parkland Health and Hospital System, Dallas, TX, USA.
  • Ko ER; Duke University, Durham, NC.
  • Ponce de Leon A; Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
  • Doernberg SB; University of California San Francisco, San Francisco, CA, USA.
  • Atmar RL; Baylor College of Medicine, Houston, TX, USA.
  • Maves RC; Naval Medical Center, San Diego, CA, USA; Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
  • Dangond F; EMD Serono Research & Development Institute, Billerica, MA, USA.
  • Ferreira J; The Emmes Company, Rockville, MD, USA.
  • Green M; The Emmes Company, Rockville, MD, USA.
  • Makowski M; The Emmes Company, Rockville, MD, USA.
  • Bonnett T; Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
  • Beresnev T; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.
Lancet Respir Med ; 9(12): 1365-1376, 2021 12.
Article em En | MEDLINE | ID: mdl-34672949
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Monofosfato de Adenosina / Alanina / Interferon beta-1a / Tratamento Farmacológico da COVID-19 Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Asia / Mexico Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Monofosfato de Adenosina / Alanina / Interferon beta-1a / Tratamento Farmacológico da COVID-19 Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Asia / Mexico Idioma: En Ano de publicação: 2021 Tipo de documento: Article