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Methyl to trifluoromethyl substitution as a strategy to increase the membrane permeability of short peptides.
Ono, Takahiro; Aikawa, Kohsuke; Okazoe, Takashi; Morimoto, Jumpei; Sando, Shinsuke.
Afiliação
  • Ono T; Department of Chemistry & Biotechnology, Graduate School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo 113-8656, Japan. jmorimoto@chembio.t.u-tokyo.ac.jp.
  • Aikawa K; Department of Chemistry & Biotechnology, Graduate School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo 113-8656, Japan. jmorimoto@chembio.t.u-tokyo.ac.jp.
  • Okazoe T; Department of Chemistry & Biotechnology, Graduate School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo 113-8656, Japan. jmorimoto@chembio.t.u-tokyo.ac.jp.
  • Morimoto J; Material Integration Laboratories, Yokohama Technical Center, AGC Inc., Yokohama 230-0045, Japan.
  • Sando S; Department of Chemistry & Biotechnology, Graduate School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo 113-8656, Japan. jmorimoto@chembio.t.u-tokyo.ac.jp.
Org Biomol Chem ; 19(43): 9386-9389, 2021 11 10.
Article em En | MEDLINE | ID: mdl-34676842
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos Idioma: En Ano de publicação: 2021 Tipo de documento: Article