Combined Anticancer Effect of Sulfated Laminaran from the Brown Alga <i>Alaria angusta</i> and Polyhydroxysteroid Glycosides from the Starfish <i>Protoreaster lincki</i> on 3D Colorectal Carcinoma HCT 116 Cell Line.

Malyarenko, Olesya S; Malyarenko, Timofey V; Usoltseva, Roza V; Surits, Valerii V; Kicha, Alla A; Ivanchina, Natalia V; Ermakova, Svetlana P

Combined Anticancer Effect of Sulfated Laminaran from the Brown Alga Alaria angusta and Polyhydroxysteroid Glycosides from the Starfish Protoreaster lincki on 3D Colorectal Carcinoma HCT 116 Cell Line.

Malyarenko, Olesya S; Malyarenko, Timofey V; Usoltseva, Roza V; Surits, Valerii V; Kicha, Alla A; Ivanchina, Natalia V; Ermakova, Svetlana P.

Afiliação

Malyarenko OS; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159 100-let Vladivostok Ave., 690022 Vladivostok, Russia.
Malyarenko TV; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159 100-let Vladivostok Ave., 690022 Vladivostok, Russia.
Usoltseva RV; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159 100-let Vladivostok Ave., 690022 Vladivostok, Russia.
Surits VV; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159 100-let Vladivostok Ave., 690022 Vladivostok, Russia.
Kicha AA; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159 100-let Vladivostok Ave., 690022 Vladivostok, Russia.
Ivanchina NV; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159 100-let Vladivostok Ave., 690022 Vladivostok, Russia.
Ermakova SP; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159 100-let Vladivostok Ave., 690022 Vladivostok, Russia.

Mar Drugs ; 19(10)2021 Sep 25.

Article em En | MEDLINE | ID: mdl-34677439

Assuntos

Antineoplásicos/farmacologia; Glucanos/farmacologia; Glicosídeos/farmacologia; Phaeophyceae; Estrelas-do-Mar; Animais; Antineoplásicos/química; Organismos Aquáticos; Proliferação de Células/efeitos dos fármacos; Sinergismo Farmacológico; Quimioterapia Combinada; Glucanos/química; Glicosídeos/química; Células HCT116/efeitos dos fármacos; Humanos

Palavras-chave

3D spheroids; AKT; Alaria angusta; HCT 116 cells; Protoreaster lincki; apoptosis induction; colorectal carcinoma; polyhydroxysteroid glycosides; sulfated laminaran

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estrelas-do-Mar / Phaeophyceae / Glucanos / Glicosídeos / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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