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Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3.
Chandrasekaran, Abinaya; Dittlau, Katarina Stoklund; Corsi, Giulia I; Haukedal, Henriette; Doncheva, Nadezhda T; Ramakrishna, Sarayu; Ambardar, Sheetal; Salcedo, Claudia; Schmidt, Sissel I; Zhang, Yu; Cirera, Susanna; Pihl, Maria; Schmid, Benjamin; Nielsen, Troels Tolstrup; Nielsen, Jørgen E; Kolko, Miriam; Kobolák, Julianna; Dinnyés, András; Hyttel, Poul; Palakodeti, Dasaradhi; Gorodkin, Jan; Muddashetty, Ravi S; Meyer, Morten; Aldana, Blanca I; Freude, Kristine K.
Afiliação
  • Chandrasekaran A; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark.
  • Dittlau KS; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark.
  • Corsi GI; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark; Center for Non-coding RNA in Technology and Health, University of Copenhagen, Frederiksberg 1871, Denmark.
  • Haukedal H; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark.
  • Doncheva NT; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark; Center for Non-coding RNA in Technology and Health, University of Copenhagen, Frederiksberg 1871, Denmark; Novo Nordisk Foundation Center for Protein Research,
  • Ramakrishna S; Institute for Stem Cell Science and Regenerative Medicine, Bangalore 560065, India; The University of Trans-Disciplinary Health Sciences and Technology, Bangalore 560064, India.
  • Ambardar S; Institute for Stem Cell Science and Regenerative Medicine, Bangalore 560065, India; National Center for Biological Sciences, Tata Institute of Fundamental Research, Bangalore 560065, India.
  • Salcedo C; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2100, Denmark.
  • Schmidt SI; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, 5000 Odense, Denmark.
  • Zhang Y; Department of Experimental Medical Science, Wallenberg Center for Molecular Medicine and Lund Stem Cell Center, Lund University, Lund 22184, Sweden.
  • Cirera S; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark.
  • Pihl M; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark.
  • Schmid B; Bioneer A/S, Hørsholm 2970, Denmark.
  • Nielsen TT; Danish Dementia Research Centre, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark.
  • Nielsen JE; Danish Dementia Research Centre, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark.
  • Kolko M; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2100, Denmark; Department of Ophthalmology, Copenhagen University Hospital, Rigshospitalet, Copenhagen 2100, Denmark.
  • Kobolák J; BioTalentum Ltd; 2100 Gödöllo, Hungary.
  • Dinnyés A; BioTalentum Ltd; 2100 Gödöllo, Hungary.
  • Hyttel P; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark.
  • Palakodeti D; Institute for Stem Cell Science and Regenerative Medicine, Bangalore 560065, India.
  • Gorodkin J; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark; Center for Non-coding RNA in Technology and Health, University of Copenhagen, Frederiksberg 1871, Denmark.
  • Muddashetty RS; Institute for Stem Cell Science and Regenerative Medicine, Bangalore 560065, India.
  • Meyer M; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, 5000 Odense, Denmark; Department of Neurology, Odense University Hospital, 5000 Odense, Denmark.
  • Aldana BI; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2100, Denmark.
  • Freude KK; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark. Electronic address: kkf@sund.ku.dk.
Stem Cell Reports ; 16(11): 2736-2751, 2021 11 09.
Article em En | MEDLINE | ID: mdl-34678206
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Astrócitos / Predisposição Genética para Doença / Demência Frontotemporal / Complexos Endossomais de Distribuição Requeridos para Transporte / Mutação Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Astrócitos / Predisposição Genética para Doença / Demência Frontotemporal / Complexos Endossomais de Distribuição Requeridos para Transporte / Mutação Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article