Dose- and Sex-Dependent Changes in Hemoglobin Oxygen Affinity by the Micronutrient 5-Hydroxymethylfurfural and &#945;-Ketoglutaric Acid.

Woyke, Simon; Mair, Norbert; Ortner, Astrid; Haller, Thomas; Ronzani, Marco; Rugg, Christopher; Ströhle, Mathias; Wintersteiger, Reinhold; Gatterer, Hannes

Dose- and Sex-Dependent Changes in Hemoglobin Oxygen Affinity by the Micronutrient 5-Hydroxymethylfurfural and α-Ketoglutaric Acid.

Woyke, Simon; Mair, Norbert; Ortner, Astrid; Haller, Thomas; Ronzani, Marco; Rugg, Christopher; Ströhle, Mathias; Wintersteiger, Reinhold; Gatterer, Hannes.

Afiliação

Woyke S; Department of Anaesthesiology and Critical Care Medicine, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Mair N; Institute of Physiology, Medical University of Innsbruck, Schöpfstraße 41, 6020 Innsbruck, Austria.
Ortner A; Institute of Pharmaceutical Sciences, University of Graz, Schubertstraße 1, 8010 Graz, Austria.
Haller T; Institute of Physiology, Medical University of Innsbruck, Schöpfstraße 41, 6020 Innsbruck, Austria.
Ronzani M; Department of Anaesthesiology and Critical Care Medicine, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Rugg C; Department of Anaesthesiology and Critical Care Medicine, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Ströhle M; Department of Anaesthesiology and Critical Care Medicine, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Wintersteiger R; Institute of Pharmaceutical Sciences, University of Graz, Schubertstraße 1, 8010 Graz, Austria.
Gatterer H; Institute of Mountain Emergency Medicine, Eurac Research, Via Ipazia 2, 39100 Bolzano, Italy.

Nutrients ; 13(10)2021 Sep 29.

Article em En | MEDLINE | ID: mdl-34684449

Assuntos

Furaldeído/análogos & derivados; Hemoglobinas/metabolismo; Ácidos Cetoglutáricos/farmacologia; Micronutrientes/farmacologia; Oxigênio/metabolismo; Adulto; Análise de Variância; Relação Dose-Resposta a Droga; Eritrócitos/efeitos dos fármacos; Eritrócitos/metabolismo; Feminino; Furaldeído/administração & dosagem; Furaldeído/farmacologia; Humanos; Ácidos Cetoglutáricos/administração & dosagem; Masculino; Micronutrientes/administração & dosagem; Ligação Proteica/efeitos dos fármacos; Fatores Sexuais; Adulto Jovem

Palavras-chave

5-HMF; Hill coefficient; P50; oxygen dissociation curve; αKG

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxigênio / Hemoglobinas / Micronutrientes / Furaldeído / Ácidos Cetoglutáricos Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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