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Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice.
Berghoff, Stefan A; Spieth, Lena; Sun, Ting; Hosang, Leon; Depp, Constanze; Sasmita, Andrew O; Vasileva, Martina H; Scholz, Patricia; Zhao, Yu; Krueger-Burg, Dilja; Wichert, Sven; Brown, Euan R; Michail, Kyriakos; Nave, Klaus-Armin; Bonn, Stefan; Odoardi, Francesca; Rossner, Moritz; Ischebeck, Till; Edgar, Julia M; Saher, Gesine.
Afiliação
  • Berghoff SA; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany. Electronic address: berghoff@em.mpg.de.
  • Spieth L; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.
  • Sun T; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany; Institute for Medical Systems Biology, Center for Molecular Neurobiology Hamburg, Hamburg, Germany.
  • Hosang L; Institute for Neuroimmunology and Multiple Sclerosis Research, University Medical Center Göttingen, Göttingen, Germany.
  • Depp C; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.
  • Sasmita AO; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.
  • Vasileva MH; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.
  • Scholz P; Department of Plant Biochemistry, Albrecht-von-Haller-Institute for Plant Sciences and Göttingen Center for Molecular Biosciences (GZMB), University of Göttingen, Göttingen, Germany.
  • Zhao Y; Institute for Medical Systems Biology, Center for Molecular Neurobiology Hamburg, Hamburg, Germany.
  • Krueger-Burg D; Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Göttingen, Germany.
  • Wichert S; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.
  • Brown ER; School of Engineering and Physical Sciences, Institute of Biological Chemistry, Biophysics and Bioengineering, James Naysmith Building, Heriot Watt University, Edinburgh, UK.
  • Michail K; School of Engineering and Physical Sciences, Institute of Biological Chemistry, Biophysics and Bioengineering, James Naysmith Building, Heriot Watt University, Edinburgh, UK.
  • Nave KA; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.
  • Bonn S; Institute for Medical Systems Biology, Center for Molecular Neurobiology Hamburg, Hamburg, Germany.
  • Odoardi F; Institute for Neuroimmunology and Multiple Sclerosis Research, University Medical Center Göttingen, Göttingen, Germany.
  • Rossner M; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.
  • Ischebeck T; Department of Plant Biochemistry, Albrecht-von-Haller-Institute for Plant Sciences and Göttingen Center for Molecular Biosciences (GZMB), University of Göttingen, Göttingen, Germany; Service Unit for Metabolomics and Lipidomics, Göttingen Center for Molecular Biosciences (GZMB), University of Göttin
  • Edgar JM; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany; Axo-glial Group, Institute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
  • Saher G; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany. Electronic address: saher@em.mpg.de.
Cell Rep ; 37(4): 109889, 2021 10 26.
Article em En | MEDLINE | ID: mdl-34706227

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colesterol / Células Precursoras de Oligodendrócitos / Remielinização / Esclerose Múltipla / Bainha de Mielina Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colesterol / Células Precursoras de Oligodendrócitos / Remielinização / Esclerose Múltipla / Bainha de Mielina Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article