Combined rs-fMRI study on brain functional imaging and mechanism of RAGE-DAMPs of depression: Evidence from MDD patients to chronic stress-induced depression models in cynomolgus monkeys and mice.

Yan, Weixin; Xie, Lingpeng; Bi, Yanmeng; Zeng, Ting; Zhao, Di; Lai, Yuqi; Gao, Tingting; Sun, Xuegang; Shi, Yafei; Dong, Zhaoyang; Wen, Ge; Gao, Lei; Lv, Zhiping

Yan, Weixin; Xie, Lingpeng; Bi, Yanmeng; Zeng, Ting; Zhao, Di; Lai, Yuqi; Gao, Tingting; Sun, Xuegang; Shi, Yafei; Dong, Zhaoyang; Wen, Ge; Gao, Lei; Lv, Zhiping.

Afiliação

Yan W; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Xie L; The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Bi Y; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Zeng T; College of Integrated Traditional Chinese and Western Medicine, Jining Medical University, Jining, Shandong, China.
Zhao D; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Lai Y; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Gao T; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Sun X; Department of General practice, The First Affiliated Hospital/School of Clinical Medicine of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
Shi Y; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Dong Z; School of Fundamental Medical Science, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Wen G; School of Nursing, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Gao L; Department of Medical Imaging, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Lv Z; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, China.

Clin Transl Med ; 11(10): e541, 2021 10.

Article em En | MEDLINE | ID: mdl-34709765

Assuntos

Alarminas/sangue; Encéfalo/diagnóstico por imagem; Transtorno Depressivo Maior/sangue; Transtorno Depressivo Maior/diagnóstico; Imageamento por Ressonância Magnética/métodos; Receptor para Produtos Finais de Glicação Avançada/sangue; Estresse Psicológico/sangue; Adolescente; Adulto; Animais; Encéfalo/fisiopatologia; Doença Crônica; Modelos Animais de Doenças; Feminino; Humanos; Inflamação/sangue; Macaca fascicularis; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Pessoa de Meia-Idade; Descanso; Estresse Fisiológico; Adulto Jovem

Palavras-chave

chronic stress; depression; functional connectivity (FC); prefrontal cortex (PFC); receptor for advanced glycation end products (RAGE); regional homogeneity (ReHo); resting-state magnetic resonance imaging (rs-fMRI)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Psicológico / Encéfalo / Imageamento por Ressonância Magnética / Transtorno Depressivo Maior / Alarminas / Receptor para Produtos Finais de Glicação Avançada Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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