Selection for constrained peptides that bind to a single target protein.

King, Andrew M; Anderson, Daniel A; Glassey, Emerson; Segall-Shapiro, Thomas H; Zhang, Zhengan; Niquille, David L; Embree, Amanda C; Pratt, Katelin; Williams, Thomas L; Gordon, D Benjamin; Voigt, Christopher A

King, Andrew M; Anderson, Daniel A; Glassey, Emerson; Segall-Shapiro, Thomas H; Zhang, Zhengan; Niquille, David L; Embree, Amanda C; Pratt, Katelin; Williams, Thomas L; Gordon, D Benjamin; Voigt, Christopher A.

Afiliação

King AM; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Anderson DA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Glassey E; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Segall-Shapiro TH; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Zhang Z; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Niquille DL; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Embree AC; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Pratt K; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Williams TL; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Gordon DB; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Voigt CA; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.

Nat Commun ; 12(1): 6343, 2021 11 03.

Article em En | MEDLINE | ID: mdl-34732700

Assuntos

Antivirais/química; Antivirais/farmacologia; Peptídeos/química; Peptídeos/farmacologia; SARS-CoV-2/efeitos dos fármacos; COVID-19/virologia; Desenho de Fármacos; Avaliação Pré-Clínica de Medicamentos; Humanos; Cinética; Modelos Moleculares; Peptídeos/genética; Ligação Proteica; SARS-CoV-2/genética; SARS-CoV-2/fisiologia; Glicoproteína da Espícula de Coronavírus/química; Glicoproteína da Espícula de Coronavírus/genética; Glicoproteína da Espícula de Coronavírus/metabolismo; Tratamento Farmacológico da COVID-19

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Peptídeos / SARS-CoV-2 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google