Febuxostat treatment attenuates oxidative stress and inflammation due to ischemia-reperfusion injury through the necrotic pathway in skin flap of animal model.

Odake, Kazuya; Tsujii, Masaya; Iino, Takahiro; Chiba, Katsura; Kataoka, Takeshi; Sudo, Akihiro

Odake, Kazuya; Tsujii, Masaya; Iino, Takahiro; Chiba, Katsura; Kataoka, Takeshi; Sudo, Akihiro.

Afiliação

Odake K; Department of Orthopaedic Surgery, Graduate School of Medicine, Mie University, Japan.
Tsujii M; Department of Orthopaedic Surgery, Graduate School of Medicine, Mie University, Japan. Electronic address: m-t727@med.mie-u.ac.jp.
Iino T; Department of Orthopaedic Surgery, Graduate School of Medicine, Mie University, Japan.
Chiba K; Department of Orthopaedic Surgery, Graduate School of Medicine, Mie University, Japan.
Kataoka T; Department of Orthopaedic Surgery, Graduate School of Medicine, Mie University, Japan.
Sudo A; Department of Orthopaedic Surgery, Graduate School of Medicine, Mie University, Japan.

Free Radic Biol Med ; 177: 238-246, 2021 12.

Article em En | MEDLINE | ID: mdl-34737143

Assuntos

Febuxostat; Traumatismo por Reperfusão; Animais; Modelos Animais de Doenças; Inflamação/tratamento farmacológico; Necrose; Estresse Oxidativo; Ratos; Ratos Sprague-Dawley; Traumatismo por Reperfusão/tratamento farmacológico

Palavras-chave

Febuxostat; Inflammation; Ischemia/reperfusion injury; Necrosis; Oxidative stress; Skin flap

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão / Febuxostat Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google