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Evaluating the Combined Impact of Temperature and Application of Interfacial Dilatational Stresses on Surface-mediated Protein Particle Formation in Monoclonal Antibody Formulations.
Griffin, Valerie P; Merritt, Kimberly; Vaclaw, Coleman; Whitaker, Neal; Volkin, David B; Ogunyankin, Maria Olu; Pace, Samantha; Dhar, Prajnaparamita.
Afiliação
  • Griffin VP; Department of Chemical and Petroleum Engineering, The University of Kansas, 1530W 15th Street, Lawrence, KS 66045, USA.
  • Merritt K; Bioengineering Program, School of Engineering, The University of Kansas, 1530W 15th Street, Lawrence, Kansas 66045, USA.
  • Vaclaw C; Bioengineering Program, School of Engineering, The University of Kansas, 1530W 15th Street, Lawrence, Kansas 66045, USA.
  • Whitaker N; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, 2030 Becker Drive, Lawrence, Kansas 66047, USA.
  • Volkin DB; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, 2030 Becker Drive, Lawrence, Kansas 66047, USA.
  • Ogunyankin MO; Department of Drug Product Development, Bristol-Myers Squibb, Inc., One Squibb Drive, New Brunswick, New Jersey, 08901, USA.
  • Pace S; Department of Drug Product Development, Bristol-Myers Squibb, Inc., One Squibb Drive, New Brunswick, New Jersey, 08901, USA.
  • Dhar P; Department of Chemical and Petroleum Engineering, The University of Kansas, 1530W 15th Street, Lawrence, KS 66045, USA; Bioengineering Program, School of Engineering, The University of Kansas, 1530W 15th Street, Lawrence, Kansas 66045, USA. Electronic address: prajnadhar@ku.edu.
J Pharm Sci ; 111(3): 680-689, 2022 03.
Article em En | MEDLINE | ID: mdl-34742729
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Membrana / Anticorpos Monoclonais Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Membrana / Anticorpos Monoclonais Idioma: En Ano de publicação: 2022 Tipo de documento: Article