A Model of Spatial Cell Development in Rat Hippocampus Based on Artificial Neural Network.

ABSTRACT

Physiological studies have shown that the hippocampal structure of rats develops at different stages, in which the place cells continue to develop during the whole juvenile period of rats and mature after the juvenile period. As the main information source of place cells, grid cells should mature earlier than place cells. In order to make better use of the biological information exhibited by the rat brain hippocampus in the environment, we propose a position cognition model based on the spatial cell development mechanism of rat hippocampus. The model uses a recurrent neural network with parametric bias (RNNPB) to simulate changes in the discharge characteristics during the development of a single stripe cell. The oscillatory interference mechanism is able to fuse the developing stripe waves, thus indirectly simulating the developmental process of the grid cells. The output of the grid cells is then used as the information input of the place cells, whose development process is simulated by BP neural network. After the place cells matured, the position matrix generated by the place cell group was used to realize the position cognition of rats in a given spatial region. The experimental results show that this model can simulate the development process of grid cells and place cells, and it can realize high precision positioning in the given space area. Moreover, the experimental effect of cognitive map construction using this model is basically consistent with the effect of RatSLAM, which verifies the validity and accuracy of the model.