Maternal background alters the penetrance of growth phenotypes and sex-specific placental adaptation of offspring sired by alcohol-exposed males.

Thomas, Kara N; Zimmel, Katherine N; Roach, Alexis N; Basel, Alison; Mehta, Nicole A; Bedi, Yudhishtar S; Golding, Michael C

Thomas, Kara N; Zimmel, Katherine N; Roach, Alexis N; Basel, Alison; Mehta, Nicole A; Bedi, Yudhishtar S; Golding, Michael C.

Afiliação

Thomas KN; Department of Veterinary Physiology & Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.
Zimmel KN; Department of Veterinary Physiology & Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.
Roach AN; Department of Veterinary Physiology & Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.
Basel A; Department of Veterinary Physiology & Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.
Mehta NA; Department of Veterinary Physiology & Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.
Bedi YS; Department of Veterinary Physiology & Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.
Golding MC; Department of Veterinary Physiology & Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.

FASEB J ; 35(12): e22035, 2021 12.

Article em En | MEDLINE | ID: mdl-34748230

Assuntos

Adaptação Fisiológica; Etanol/toxicidade; Transtornos do Espectro Alcoólico Fetal/patologia; Retardo do Crescimento Fetal/patologia; Herança Paterna; Penetrância; Placenta/fisiopatologia; Animais; Epigênese Genética; Feminino; Transtornos do Espectro Alcoólico Fetal/etiologia; Retardo do Crescimento Fetal/induzido quimicamente; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Fenótipo; Gravidez; Fatores Sexuais; Transcriptoma

Palavras-chave

RRID:IMSR_CRL:22; RRID:IMSR_JAX:000664; RRID:SCR_002798; developmental programming; fetal alcohol spectrum disorder (FASDs); genetic background; mitochondrial disfunction; oxidative phosphorylation; paternal epigenetic inheritance; placental adaptation; placental dysfunction; preconception exposure

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Placenta / Adaptação Fisiológica / Penetrância / Etanol / Transtornos do Espectro Alcoólico Fetal / Retardo do Crescimento Fetal / Herança Paterna Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Pregnancy Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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