Molecular recognition of two bioactive coumarin derivatives 7-hydroxycoumarin and 4-methyl-7-hydroxycoumarin by hen egg white lysozyme: Exploring the binding mechanism, thermodynamic parameters and structural changes using multispectroscopic and computational approaches.

Lyndem, Sona; Gazi, Rabiul; Jana, Madhurima; Belwal, Vinay Kumar; Singha Roy, Atanu

Lyndem, Sona; Gazi, Rabiul; Jana, Madhurima; Belwal, Vinay Kumar; Singha Roy, Atanu.

Afiliação

Lyndem S; Department of Chemistry, National Institute of Technology, Meghalaya, Shillong, India.
Gazi R; Department of Chemistry, Molecular Simulation Laboratory, National Institute of Technology, Rourkela, Odisha, India.
Jana M; Department of Chemistry, Molecular Simulation Laboratory, National Institute of Technology, Rourkela, Odisha, India.
Belwal VK; Department of Bioscience and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, India.
Singha Roy A; Department of Chemistry, National Institute of Technology, Meghalaya, Shillong, India.

J Biomol Struct Dyn ; 40(24): 13872-13888, 2022.

Article em En | MEDLINE | ID: mdl-34751096

Assuntos

Cumarínicos; Muramidase; Simulação de Acoplamento Molecular; Muramidase/química; Clara de Ovo; Termodinâmica; Proteínas de Transporte/metabolismo; Umbeliferonas; Ligação Proteica

Palavras-chave

4-methyl-7-hydroxycoumarin; 7-hydroxycoumarin; Hen egg white lysozyme; docking; fluorescence; quenching

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Muramidase / Cumarínicos Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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