Tumor-derived extracellular vesicles regulate tumor-infiltrating regulatory T cells via the inhibitory immunoreceptor CD300a.

Nakazawa, Yuta; Nishiyama, Nanako; Koizumi, Hitoshi; Kanemaru, Kazumasa; Nakahashi-Oda, Chigusa; Shibuya, Akira

Nakazawa, Yuta; Nishiyama, Nanako; Koizumi, Hitoshi; Kanemaru, Kazumasa; Nakahashi-Oda, Chigusa; Shibuya, Akira.

Afiliação

Nakazawa Y; Department of Immunology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Nishiyama N; Doctoral Program of Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan.
Koizumi H; Department of Immunology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Kanemaru K; Doctoral Program of Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan.
Nakahashi-Oda C; Department of Immunology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Shibuya A; Doctoral Program of Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan.

Elife ; 102021 11 09.

Article em En | MEDLINE | ID: mdl-34751648

Assuntos

Vesículas Extracelulares/fisiologia; Receptores Imunológicos/metabolismo; Linfócitos T Reguladores/imunologia; Animais; Camundongos; Camundongos Endogâmicos C57BL; Receptores Imunológicos/genética

Palavras-chave

CD300a; IFN-b; cancer biology; dendritic cells; immunology; immunoreceptor; inflammation; mouse; tumor-derived extracellular vesicles; tumor-infiltrating regulatory T cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Imunológicos / Linfócitos T Reguladores / Vesículas Extracelulares Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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