Toward modeling metabolic state from single-cell transcriptomics.

Hrovatin, Karin; Fischer, David S; Theis, Fabian J

Hrovatin, Karin; Fischer, David S; Theis, Fabian J.

Afiliação

Hrovatin K; Institute of Computational Biology, Helmholtz Center Munich, Ingolstaedter Landstraße 1, Neuherberg, 85764, Germany; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Alte Akademie 8, Freising, 85354, Germany. Electronic address: karin.hrovatin@helmholtz-muenchen.de.
Fischer DS; Institute of Computational Biology, Helmholtz Center Munich, Ingolstaedter Landstraße 1, Neuherberg, 85764, Germany; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Alte Akademie 8, Freising, 85354, Germany. Electronic address: david.fischer@helmholtz-muenchen.de.
Theis FJ; Institute of Computational Biology, Helmholtz Center Munich, Ingolstaedter Landstraße 1, Neuherberg, 85764, Germany; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Alte Akademie 8, Freising, 85354, Germany; Department of Mathematics, Technical University of Munich, Boltzmannstr. 3, Garching bei München, 85748, Germany. Electronic address: fabian.theis@helmholtz-muenchen.de.

Mol Metab ; 57: 101396, 2022 03.

Article em En | MEDLINE | ID: mdl-34785394

Assuntos

Modelos Biológicos; Transcriptoma; Cinética; Redes e Vias Metabólicas/genética

Palavras-chave

Constraint-based modeling; Kinetic modeling; Metabolic modeling; Pathway analysis; Single-cell RNA-seq

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcriptoma / Modelos Biológicos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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