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A novel silicone derivative of natural osalmid (DCZ0858) exerts anti-multiple myeloma activity by promoting cell apoptosis and inhibiting cell cycle and mTOR signaling.
Bu, Wenxuan; Li, Bo; Feng, Lijin; Feng, Qilin; Hu, Ke; Xu, Zhijian; Wang, Yingcong; Xi, Mengyu; Wang, Houcai; Yang, Guang; Wu, Xiaosong; Zhu, Weiliang; Shi, Jumei.
Afiliação
  • Bu W; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
  • Li B; Nanjing Medical University Nanjing 211100, China.
  • Feng L; CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences Shanghai 201203, China.
  • Feng Q; Department of Pathology, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
  • Hu K; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
  • Xu Z; Nanjing Medical University Nanjing 211100, China.
  • Wang Y; CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences Shanghai 201203, China.
  • Xi M; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
  • Wang H; CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences Shanghai 201203, China.
  • Yang G; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
  • Wu X; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
  • Zhu W; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
  • Shi J; CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences Shanghai 201203, China.
Am J Transl Res ; 13(10): 11439-11449, 2021.
Article em En | MEDLINE | ID: mdl-34786070
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article