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Abnormal accumulation of lipid droplets in neurons induces the conversion of alpha-Synuclein to proteolytic resistant forms in a Drosophila model of Parkinson's disease.
Girard, Victor; Jollivet, Florence; Knittelfelder, Oskar; Celle, Marion; Arsac, Jean-Noel; Chatelain, Gilles; Van den Brink, Daan M; Baron, Thierry; Shevchenko, Andrej; Kühnlein, Ronald P; Davoust, Nathalie; Mollereau, Bertrand.
Afiliação
  • Girard V; Laboratory of Biology and Modelling of the Cell, UMR5239 CNRS/ENS de Lyon, INSERM U1210, UMS 3444 Biosciences Lyon Gerland, University of Lyon, Lyon, France.
  • Jollivet F; Laboratory of Biology and Modelling of the Cell, UMR5239 CNRS/ENS de Lyon, INSERM U1210, UMS 3444 Biosciences Lyon Gerland, University of Lyon, Lyon, France.
  • Knittelfelder O; Max-Planck-Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
  • Celle M; Laboratory of Biology and Modelling of the Cell, UMR5239 CNRS/ENS de Lyon, INSERM U1210, UMS 3444 Biosciences Lyon Gerland, University of Lyon, Lyon, France.
  • Arsac JN; Neurodegenerative Disease Unit; French Agency for Food, Environmental and Occupational Health & Safety Laboratory (Anses) of Lyon, University of Lyon, Lyon, France.
  • Chatelain G; Laboratory of Biology and Modelling of the Cell, UMR5239 CNRS/ENS de Lyon, INSERM U1210, UMS 3444 Biosciences Lyon Gerland, University of Lyon, Lyon, France.
  • Van den Brink DM; Laboratory of Biology and Modelling of the Cell, UMR5239 CNRS/ENS de Lyon, INSERM U1210, UMS 3444 Biosciences Lyon Gerland, University of Lyon, Lyon, France.
  • Baron T; Plant Systems Physiology, Radboud Institute for Biological and Environmental Sciences, Radboud University, Nijmegen, The Netherlands.
  • Shevchenko A; Neurodegenerative Disease Unit; French Agency for Food, Environmental and Occupational Health & Safety Laboratory (Anses) of Lyon, University of Lyon, Lyon, France.
  • Kühnlein RP; Max-Planck-Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
  • Davoust N; Institute of Molecular Biosciences, University of Graz, Graz, Austria.
  • Mollereau B; BioTechMed-Graz, Graz, Austria.
PLoS Genet ; 17(11): e1009921, 2021 11.
Article em En | MEDLINE | ID: mdl-34788284
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Alfa-Sinucleína / Metabolismo dos Lipídeos / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Alfa-Sinucleína / Metabolismo dos Lipídeos / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article