Research-Based Product Innovation to Address Critical Unmet Needs of Patients with Inflammatory Bowel Diseases.

Honig, Gerard; Larkin, Paul B; Heller, Caren; Hurtado-Lorenzo, Andrés

Honig, Gerard; Larkin, Paul B; Heller, Caren; Hurtado-Lorenzo, Andrés.

Afiliação

Honig G; Crohn's & Colitis Foundation, New York, NY, USA.
Larkin PB; Crohn's & Colitis Foundation, New York, NY, USA.
Heller C; Crohn's & Colitis Foundation, New York, NY, USA.
Hurtado-Lorenzo A; Crohn's & Colitis Foundation, New York, NY, USA.

Inflamm Bowel Dis ; 27(Suppl 2): S1-S16, 2021 11 15.

Article em En | MEDLINE | ID: mdl-34791292

We highlight the pipeline of investigational therapies, diagnostics, and devices with potential to address pressing unmet needs of patients with inflammatory bowel diseases, including biomarkers for prognosis and treatment response, restoration of eubiosis and mucosal healing, neuromodulation, and improved control of inflammation and disease complications.

Assuntos

Anti-Inflamatórios/uso terapêutico; Necessidades e Demandas de Serviços de Saúde; Imunossupressores/uso terapêutico; Doenças Inflamatórias Intestinais/terapia; Biomarcadores/sangue; Colite; Doença de Crohn; Humanos

Palavras-chave

IBD therapies; anti-inflammatory; barrier integrity; behavioral therapy; biomarkers; complications; eubiosis; gut-targeted drug delivery; mucosal healing; neuroinflammation; neuromodulation; precision medicine; preclinical development

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Necessidades e Demandas de Serviços de Saúde / Imunossupressores / Anti-Inflamatórios Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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