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Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Friedrich, Nikolas; Stiegeler, Emanuel; Glögl, Matthias; Lemmin, Thomas; Hansen, Simon; Kadelka, Claus; Wu, Yufan; Ernst, Patrick; Maliqi, Liridona; Foulkes, Caio; Morin, Mylène; Eroglu, Mustafa; Liechti, Thomas; Ivan, Branislav; Reinberg, Thomas; Schaefer, Jonas V; Karakus, Umut; Ursprung, Stephan; Mann, Axel; Rusert, Peter; Kouyos, Roger D; Robinson, John A; Günthard, Huldrych F; Plückthun, Andreas; Trkola, Alexandra.
Afiliação
  • Friedrich N; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.
  • Stiegeler E; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.
  • Glögl M; Roche Diagnostics GmbH, Nonnenwald 2, 82377, Penzberg, Deutschland.
  • Lemmin T; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.
  • Hansen S; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.
  • Kadelka C; Department of Computer Science, ETH Zurich, Zurich, Switzerland.
  • Wu Y; Euler Institute, Faculty of Biomedicine, Università della Svizzera italiana (USI), Lugano, Switzerland.
  • Ernst P; Department of Biochemistry, University of Zurich (UZH), Zurich, Switzerland.
  • Maliqi L; NGM Bio, 333 Oysterpoint Blvd, South San Francisco, CA, 94080, USA.
  • Foulkes C; Department of Mathematics, Iowa State University, Ames, IA, USA.
  • Morin M; Department of Biochemistry, University of Zurich (UZH), Zurich, Switzerland.
  • Eroglu M; Innovent Biologics Inc, 168 Dongping Street, Suzhou Industrial Park, 215123, China.
  • Liechti T; Department of Biochemistry, University of Zurich (UZH), Zurich, Switzerland.
  • Ivan B; Office Research and Teaching, Medical Faculty, University of Zurich, Zurich, Switzerland.
  • Reinberg T; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.
  • Schaefer JV; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.
  • Karakus U; Department of Chemistry, University of Zurich (UZH), Zurich, Switzerland.
  • Ursprung S; BeiGene Switzerland GmbH, Aeschengraben 27, 4051, Basel, Switzerland.
  • Mann A; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.
  • Rusert P; Janssen Vaccines AG, Rehhagstrasse 79, 3018, Bern, Switzerland.
  • Kouyos RD; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.
  • Robinson JA; ImmunoTechnology Section, Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA.
  • Günthard HF; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.
  • Plückthun A; Laboratory Medicine, Division of Clinical Chemistry, University Hospital Basel, Basel, Switzerland.
  • Trkola A; Department of Biochemistry, University of Zurich (UZH), Zurich, Switzerland.
Nat Commun ; 12(1): 6705, 2021 11 18.
Article em En | MEDLINE | ID: mdl-34795280
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Conformação Proteica / Anticorpos Anti-HIV / HIV-1 / Produtos do Gene env do Vírus da Imunodeficiência Humana / Anticorpos Neutralizantes Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Conformação Proteica / Anticorpos Anti-HIV / HIV-1 / Produtos do Gene env do Vírus da Imunodeficiência Humana / Anticorpos Neutralizantes Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article