A coarse-grained NADH redox model enables inference of subcellular metabolic fluxes from fluorescence lifetime imaging.

Yang, Xingbo; Ha, Gloria; Needleman, Daniel J

Yang, Xingbo; Ha, Gloria; Needleman, Daniel J.

Afiliação

Yang X; Department of Molecular and Cellular Biology and John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, United States.
Ha G; Department of Molecular and Cellular Biology and John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, United States.
Needleman DJ; Department of Molecular and Cellular Biology and John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, United States.

Elife ; 102021 11 22.

Article em En | MEDLINE | ID: mdl-34806591

Assuntos

Mitocôndrias; NAD; Animais; Camundongos; Microscopia de Fluorescência; Mitocôndrias/metabolismo; NAD/metabolismo; Imagem Óptica; Oxirredução

Palavras-chave

FLIM; NADH; biochemistry; chemical biology; coarse-grained model; human; metabolic flux; mitochondria; mouse; oocytes; physics of living systems

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mitocôndrias / NAD Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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